| Title |
Prevalence of hepatitis B and C infection in persons living with HIV enrolled in care in Rwanda
|
|---|---|
| Published in |
BMC Infectious Diseases, May 2017
|
| DOI | 10.1186/s12879-017-2422-9 |
| Pubmed ID | |
| Authors |
Justine Umutesi, Bryony Simmons, Jean D. Makuza, Donatha Dushimiyimana, Aimable Mbituyumuremyi, Jean Marie Uwimana, Nathan Ford, Edward J. Mills, Sabin Nsanzimana |
| Abstract |
Hepatitis B (HBV) and C (HCV) are important causes of morbidity and mortality in people living with human immunodeficiency virus (HIV). The burden of these co-infections in sub-Saharan Africa is still unclear. We estimated the prevalence of the hepatitis B surface antigen (HBsAg) and hepatitis C antibody (HCVAb) among HIV-infected individuals in Rwanda and identified factors associated with infection. Between January 2016 and June 2016, we performed systematic screening for HBsAg and HCVAb among HIV-positive individuals enrolled at public and private HIV facilities across Rwanda. Results were analyzed to determine marker prevalence and variability by demographic factors. Overall, among 117,258 individuals tested, the prevalence of HBsAg and HCVAb was 4.3% (95% confidence interval [CI] (4.2-4.4) and 4.6% (95% CI 4.5-4.7) respectively; 182 (0.2%) HIV+ individuals were co-infected with HBsAg and HCVAb. Prevalence was higher in males (HBsAg, 5.4% [5.1-5.6] vs. 3.7% [3.5-3.8]; HCVAb, 5.0% [4.8-5.2] vs. 4.4% [4.3-4.6]) and increased with age; HCVAb prevalence was significantly higher in people aged ≥65 years (17.8% [16.4-19.2]). Prevalence varied geographically. HBV and HCV co-infections are common among HIV-infected individuals in Rwanda. It is important that viral hepatitis prevention and treatment activities are scaled-up to control further transmission and reduce the burden in this population. Particular efforts should be made to conduct targeted screening of males and the older population. Further assessment is required to determine rates of HBV and HCV chronicity among HIV-infected individuals and identify effective strategies to link individuals to care and treatment. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 136 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 29 | 21% |
| Student > Bachelor | 24 | 18% |
| Researcher | 11 | 8% |
| Student > Postgraduate | 8 | 6% |
| Student > Ph. D. Student | 5 | 4% |
| Other | 16 | 12% |
| Unknown | 43 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 18% |
| Nursing and Health Professions | 15 | 11% |
| Immunology and Microbiology | 12 | 9% |
| Biochemistry, Genetics and Molecular Biology | 8 | 6% |
| Agricultural and Biological Sciences | 7 | 5% |
| Other | 18 | 13% |
| Unknown | 51 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2018.
All research outputs
#7,281,255
of 22,971,207 outputs
Outputs from BMC Infectious Diseases
#2,416
of 7,709 outputs
Outputs of similar age
#115,179
of 310,778 outputs
Outputs of similar age from BMC Infectious Diseases
#69
of 187 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 7,709 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has gotten more attention than average, scoring higher than 67% of its peers.
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We're also able to compare this research output to 187 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.