| Title |
Dye-based mito-thermometry and its application in thermogenesis of brown adipocytes
|
|---|---|
| Published in |
Biophysics Reports, May 2017
|
| DOI | 10.1007/s41048-017-0039-6 |
| Pubmed ID | |
| Authors |
Tao-Rong Xie, Chun-Feng Liu, Jian-Sheng Kang |
| Abstract |
Mitochondrion is the main intracellular site for thermogenesis and attractive energy expenditure targeting for obesity therapy. Here, we develop a method of mitochondrial thermometry based on Rhodamine B methyl ester, which equilibrates as a thermosensitive mixture of nonfluorescent and fluorescent resonance forms. Using this approach, we are able to demonstrate that the efficacy of norepinephrine-induced thermogenesis is low, and measure the maximum transient rate of temperature increase in brown adipocytes. The online version of this article (doi:10.1007/s41048-017-0039-6) contains supplementary material, which is available to authorized users. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 28 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 14% |
| Researcher | 4 | 14% |
| Professor | 3 | 11% |
| Student > Master | 3 | 11% |
| Student > Bachelor | 1 | 4% |
| Other | 3 | 11% |
| Unknown | 10 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Physics and Astronomy | 5 | 18% |
| Biochemistry, Genetics and Molecular Biology | 4 | 14% |
| Agricultural and Biological Sciences | 2 | 7% |
| Chemistry | 2 | 7% |
| Nursing and Health Professions | 1 | 4% |
| Other | 4 | 14% |
| Unknown | 10 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2017.
All research outputs
#19,637,467
of 24,153,435 outputs
Outputs from Biophysics Reports
#36
of 53 outputs
Outputs of similar age
#241,034
of 313,289 outputs
Outputs of similar age from Biophysics Reports
#1
of 1 outputs
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