Title |
REM-Schlaf-Verhaltensstörung als prodromales Stadium von α-Synukleinopathien
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Published in |
Der Nervenarzt, January 2014
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DOI | 10.1007/s00115-013-3891-8 |
Pubmed ID | |
Authors |
W.H. Oertel, C. Depboylu, M. Krenzer, D. Vadasz, V. Ries, F. Sixel-Döring, G. Mayer |
Abstract |
Rapid eye movement (REM) sleep behavior disorder (RBD) is defined as a parasomnia characterized by loss of REM sleep-associated atonia and the presence of motor activity during dreaming typically presenting with an aggressive dream content. Epidemiological data on the prevalence of RBD are insufficient but it can be idiopathic or symptomatic. A video-audio polysomnography is essential for diagnosis. Clonazepam and melatonin are available as pharmaceutical treatment. Recent studies demonstrated that individuals suffering from idiopathic RBD carry a high specific risk (up to 80 %) for developing a neurodegenerative disorder of the α-synucleinopathy type (e.g. Parkinson's disease, dementia with Lewy bodies and multiple system atrophy) within 10-20 years. The current article provides a short overview of symptoms, epidemiology, pathophysiology, diagnosis and therapy of RBD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 46 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 8 | 17% |
Student > Master | 5 | 10% |
Student > Doctoral Student | 4 | 8% |
Researcher | 4 | 8% |
Student > Ph. D. Student | 4 | 8% |
Other | 7 | 15% |
Unknown | 16 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 27% |
Psychology | 8 | 17% |
Neuroscience | 6 | 13% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Business, Management and Accounting | 1 | 2% |
Other | 3 | 6% |
Unknown | 15 | 31% |