| Title |
The Influence of Energetic Factors on Biomarkers of Postmenopausal Breast Cancer Risk
|
|---|---|
| Published in |
Current Nutrition Reports, December 2013
|
| DOI | 10.1007/s13668-013-0069-8 |
| Pubmed ID | |
| Authors |
Heather K. Neilson, Shannon M. Conroy, Christine M. Friedenreich |
| Abstract |
Strong and consistent evidence exists that physical activity reduces breast cancer risk by 10-25 %, and several proposed biologic mechanisms have now been investigated in randomized, controlled, exercise intervention trials. Leading hypothesized mechanisms relating to postmenopausal breast cancer include adiposity, endogenous sex hormones, insulin resistance, and chronic low-grade inflammation. In addition, other pathways are emerging as potentially important, including those involving oxidative stress and telomere length, global DNA hypomethylation, immune function, and vitamin D exposure. Recent exercise trials in overweight/obese postmenopausal women implicate weight loss as a mechanism whereby exercise induces favorable changes in circulating estradiol levels and other biomarkers as well. Still it is plausible that some exercise-induced biomarker changes do not require loss of body fat, whereas others depend on abdominal fat loss. We highlight the latest findings from randomized, controlled trials of healthy postmenopausal women, relating exercise to proposed biomarkers for postmenopausal breast cancer risk. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 1% |
| Unknown | 134 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 28 | 21% |
| Student > Bachelor | 15 | 11% |
| Researcher | 10 | 7% |
| Student > Ph. D. Student | 9 | 7% |
| Student > Postgraduate | 7 | 5% |
| Other | 22 | 16% |
| Unknown | 45 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 22% |
| Sports and Recreations | 12 | 9% |
| Agricultural and Biological Sciences | 11 | 8% |
| Nursing and Health Professions | 10 | 7% |
| Biochemistry, Genetics and Molecular Biology | 8 | 6% |
| Other | 17 | 13% |
| Unknown | 48 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2014.
All research outputs
#18,360,179
of 22,739,983 outputs
Outputs from Current Nutrition Reports
#254
of 325 outputs
Outputs of similar age
#232,151
of 307,716 outputs
Outputs of similar age from Current Nutrition Reports
#3
of 5 outputs
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