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Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies

Overview of attention for article published in Canadian Medical Association Journal, May 2017
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

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Title
Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies
Published in
Canadian Medical Association Journal, May 2017
DOI 10.1503/cmaj.160706
Pubmed ID
Authors

Christine S. Tsilas, Russell J. de Souza, Sonia Blanco Mejia, Arash Mirrahimi, Adrian I. Cozma, Viranda H. Jayalath, Vanessa Ha, Reem Tawfik, Marco Di Buono, Alexandra L. Jenkins, Lawrence A. Leiter, Thomas M.S. Wolever, Joseph Beyene, Tauseef Khan, Cyril W.C. Kendall, David J.A. Jenkins, John L. Sievenpiper

Abstract

Sugar-sweetened beverages are associated with type 2 diabetes. To assess whether this association holds for the fructose-containing sugars they contain, we conducted a systematic review and meta-analysis of prospective cohort studies. We searched MEDLINE, Embase, CINAHL and the Cochrane Library (through June 2016). We included prospective cohort studies that assessed the relation of fructose-containing sugars with incident type 2 diabetes. Two independent reviewers extracted relevant data and assessed risk of bias. We pooled risk ratios (RRs) using random effects meta-analyses. The overall quality of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. Fiffeen prospective cohort studies (251 261 unique participants, 16 416 cases) met the eligibility criteria, comparing the highest intake (median 137, 35.2 and 78 g/d) with the lowest intake (median 65, 9.7 and 25.8 g/d) of total sugars, fructose and sucrose, respectively. Although there was no association of total sugars (RR 0.91, 95% confidence interval [CI] 0.76-1.09) or fructose (RR 1.04, 95% CI 0.84-1.29) with type 2 diabetes, sucrose was associated with a decreased risk of type 2 diabetes (RR 0.89, 95% CI 0.80-0.98). Our confidence in the estimates was limited by evidence of serious inconsistency between studies for total sugars and fructose, and serious imprecision in the pooled estimates for all 3 sugar categories. Current evidence does not allow us to conclude that fructose-containing sugars independent of food form are associated with increased risk of type 2 diabetes. Further research is likely to affect our estimates. ClinicalTrials.gov, no. NCT01608620.

X Demographics

X Demographics

The data shown below were collected from the profiles of 219 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 224 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 224 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 35 16%
Student > Bachelor 34 15%
Student > Ph. D. Student 24 11%
Researcher 22 10%
Student > Postgraduate 14 6%
Other 34 15%
Unknown 61 27%
Readers by discipline Count As %
Medicine and Dentistry 58 26%
Nursing and Health Professions 35 16%
Biochemistry, Genetics and Molecular Biology 17 8%
Agricultural and Biological Sciences 9 4%
Social Sciences 9 4%
Other 21 9%
Unknown 75 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 210. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2023.
All research outputs
#189,529
of 25,757,133 outputs
Outputs from Canadian Medical Association Journal
#344
of 9,546 outputs
Outputs of similar age
#3,886
of 328,387 outputs
Outputs of similar age from Canadian Medical Association Journal
#12
of 121 outputs
Altmetric has tracked 25,757,133 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,546 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 34.3. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,387 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 121 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.