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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A Promiscuous Intermediate Underlies the Evolution of LEAFY DNA Binding Specificity
|
|---|---|
| Published in |
Science, January 2014
|
| DOI | 10.1126/science.1248229 |
| Pubmed ID | |
| Authors |
Camille Sayou, Marie Monniaux, Max H. Nanao, Edwige Moyroud, Samuel F. Brockington, Emmanuel Thévenon, Hicham Chahtane, Norman Warthmann, Michael Melkonian, Yong Zhang, Gane Ka-Shu Wong, Detlef Weigel, François Parcy, Renaud Dumas |
| Abstract |
Transcription factors (TFs) are key players in evolution. Changes affecting their function can yield novel life forms but may also have deleterious effects. Consequently, gene duplication events that release one gene copy from selective pressure are thought to be the common mechanism by which TFs acquire new activities. Here, we show that LEAFY, a major regulator of flower development and cell division in land plants, underwent changes to its DNA binding specificity, even though plant genomes generally contain a single copy of the LEAFY gene. We examined how these changes occurred at the structural level and identify an intermediate LEAFY form in hornworts that appears to adopt all different specificities. This promiscuous intermediate could have smoothed the evolutionary transitions, thereby allowing LEAFY to evolve new binding specificities while remaining a single-copy gene. |
X Demographics
The data shown below were collected from the profiles of 35 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 3 | 9% |
| United States | 3 | 9% |
| Switzerland | 2 | 6% |
| Japan | 2 | 6% |
| Canada | 2 | 6% |
| France | 1 | 3% |
| Argentina | 1 | 3% |
| Norway | 1 | 3% |
| Spain | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 19 | 54% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 54% |
| Scientists | 13 | 37% |
| Practitioners (doctors, other healthcare professionals) | 2 | 6% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 292 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 1% |
| Germany | 2 | <1% |
| France | 2 | <1% |
| Canada | 2 | <1% |
| Netherlands | 1 | <1% |
| Czechia | 1 | <1% |
| New Zealand | 1 | <1% |
| Portugal | 1 | <1% |
| Estonia | 1 | <1% |
| Other | 3 | 1% |
| Unknown | 274 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 86 | 29% |
| Researcher | 55 | 19% |
| Student > Bachelor | 29 | 10% |
| Professor | 26 | 9% |
| Student > Master | 26 | 9% |
| Other | 43 | 15% |
| Unknown | 27 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 187 | 64% |
| Biochemistry, Genetics and Molecular Biology | 58 | 20% |
| Chemistry | 4 | 1% |
| Computer Science | 3 | 1% |
| Medicine and Dentistry | 3 | 1% |
| Other | 5 | 2% |
| Unknown | 32 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 42. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2024.
All research outputs
#1,007,489
of 26,017,215 outputs
Outputs from Science
#18,912
of 83,593 outputs
Outputs of similar age
#10,808
of 323,899 outputs
Outputs of similar age from Science
#183
of 824 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 83,593 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 65.8. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,899 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 824 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.