| Title |
A 4-year follow-up of patients with medication-overuse headache previously included in a randomized multicentre study
|
|---|---|
| Published in |
The Journal of Headache and Pain, January 2011
|
| DOI | 10.1007/s10194-010-0285-1 |
| Pubmed ID | |
| Authors |
Knut Hagen, Claus Albretsen, Steinar T. Vilming, Rolf Salvesen, Marit Grønning, Grethe Helde, Gøril Gravdahl, John-Anker Zwart, Lars Jacob Stovner |
| Abstract |
The aim of this study was to evaluate the long-term outcome in 61 patients with medication-overuse headache (MOH) who 4 years previously had been included in a randomized open-label prospective multicentre study. Sixty patients still alive after 4 years were invited to a follow-up investigation. Fifty patients (83%) participated. Sixteen visited a neurologist, 22 were interviewed through telephone, 2 gave response by a letter, and 10 were evaluated through hospital records. The influence of baseline characteristics on outcome 4 years later was evaluated by non-parametric tests. p values below 0.01 were considered significant. At follow-up, the 50 persons had a mean reduction of 6.5 headache days/month (p < 0.001) and 9.5 acute headache medication days/month (p < 0.001) compared to baseline. Headache index/month was reduced from 449 to 321 (p < 0.001). Sixteen persons (32%) were considered as responders due to a ≥50% reduction in headache frequency from baseline, whereas 17 (34%) persons met the criteria for MOH. None of the baseline characteristics consistently influenced all five outcome measures. Total Hospital Anxiety and Depression Scale (HADS) score at baseline was predictors (p < 0.005) for being a responder after 4 years. At 4 years' follow-up, one-third of the 50 MOH patients had ≥50% reduction in headache frequency from baseline. A low total HADS score at baseline was associated with the most favorable outcome. |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 2% |
| France | 1 | 2% |
| Unknown | 49 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 31% |
| Student > Master | 6 | 12% |
| Researcher | 6 | 12% |
| Student > Bachelor | 4 | 8% |
| Other | 4 | 8% |
| Other | 4 | 8% |
| Unknown | 11 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 35% |
| Psychology | 4 | 8% |
| Nursing and Health Professions | 3 | 6% |
| Immunology and Microbiology | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 6 | 12% |
| Unknown | 16 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2012.
All research outputs
#7,866,480
of 23,849,058 outputs
Outputs from The Journal of Headache and Pain
#708
of 1,417 outputs
Outputs of similar age
#56,187
of 185,364 outputs
Outputs of similar age from The Journal of Headache and Pain
#8
of 16 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
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