Title |
A randomised controlled trial of delayed cord clamping in very low birth weight preterm infants
|
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Published in |
European Journal of Pediatrics, September 2000
|
DOI | 10.1007/pl00008345 |
Pubmed ID | |
Authors |
Heike Rabe, Anne Wacker, Georg Hülskamp, Isabell Hörnig-Franz, Anne Schulze-Everding, Erik Harms, Ulrich Cirkel, Frank Louwen, Ralf Witteler, Hermann P. G. Schneider |
Abstract |
This study was carried out to assess the feasibility of late cord clamping of 45 s in preterm infants delivered mainly by caesarean section and the effects on postpartal adaptation and anaemia of prematurity. Prior to delivery, 40 infants of < 33 gestational weeks were randomised to either 20 s or 45 s of late cord clamping. After the first shoulder was delivered, oxytocin was given intravenously to the mother in order to enhance placento-fetal transfusion while the infant was held below the level of the placenta. The 20 infants in group 1 (20 s) had a mean birth weight of 1070 g and a mean gestational age of 29 + 4/7 weeks versus 1190 g and 30 weeks in group 2 (45 s). On day 42 of life there were ten infants without transfusions in group 2 versus three in group 1 (P < 0.05). Out of the 20 infants in group 1, 19 and 15/19 in group 2 were delivered by caesarean section. There were no significant differences in Apgar scores, temperature on admission, heart rate, blood pressure and requirements for artificial ventilation. |
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Geographical breakdown
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Unknown | 73 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 10 | 13% |
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Professor > Associate Professor | 8 | 10% |
Student > Postgraduate | 7 | 9% |
Other | 19 | 25% |
Unknown | 12 | 16% |
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