Title |
Meta-Analysis Comparing Carvedilol Versus Metoprolol for the Prevention of Postoperative Atrial Fibrillation Following Coronary Artery Bypass Grafting
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Published in |
American Journal of Cardiology, November 2013
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DOI | 10.1016/j.amjcard.2013.10.020 |
Pubmed ID | |
Authors |
James J. DiNicolantonio, Craig J. Beavers, Arthur R. Menezes, Carl J. Lavie, James H. O'Keefe, Pascal Meier, András Vorobcsuk, Dániel Aradi, András Komócsi, Saurav Chatterjee, Fabrizio D'Ascenzo, Mauro Gasparini, Jasper Brugts, Giuseppe Biondi-Zoccai |
Abstract |
A systematic review and meta-analysis was performed to evaluate the effects of carvedilol versus metoprolol on the incidence of postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting in randomized controlled trials. Ovid MEDLINE, PubMed, CENTRAL, and Excepta Medica (EMBASE) were searched up to March 2013 for suitable randomized controlled trials. Data were pooled using random-effects model for pairwise analyses. A total of 4 trials with 601 patients were included in this analysis. Pairwise analyses showed that compared with metoprolol, carvedilol significantly reduced the incidence of postoperative atrial fibrillation (odds ratio 0.50, 95% confidence interval 0.32 to 0.80). In conclusion, compared with metoprolol, carvedilol significantly reduces the incidence of postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
Bosnia and Herzegovina | 1 | 2% |
Italy | 1 | 2% |
Unknown | 57 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 11 | 18% |
Other | 8 | 13% |
Student > Bachelor | 6 | 10% |
Student > Master | 6 | 10% |
Student > Ph. D. Student | 5 | 8% |
Other | 11 | 18% |
Unknown | 13 | 22% |
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Medicine and Dentistry | 36 | 60% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Agricultural and Biological Sciences | 3 | 5% |
Sports and Recreations | 1 | 2% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Other | 2 | 3% |
Unknown | 13 | 22% |