| Title |
Genome-wide analysis reveals downregulation of miR-379/miR-656 cluster in human cancers
|
|---|---|
| Published in |
Biology Direct, April 2013
|
| DOI | 10.1186/1745-6150-8-10 |
| Pubmed ID | |
| Authors |
Saurabh V Laddha, Subhashree Nayak, Deepanjan Paul, Rajasekhara Reddy, Charu Sharma, Prerana Jha, Manoj Hariharan, Anurag Agrawal, Shantanu Chowdhury, Chitra Sarkar, Arijit Mukhopadhyay |
| Abstract |
MicroRNAs (miRNAs) are non-uniformly distributed in genomes and ~30% of the miRNAs in the human genome are clustered. In this study we have focused on the imprinted miRNA cluster miR-379/miR-656 on 14q32.31 (hereafter C14) to test their coordinated function. We have analyzed expression profile of >1000 human miRNAs in >1400 samples representing seven different human tissue types obtained from cancer patients along with matched and unmatched controls. |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 2% |
| Italy | 1 | 2% |
| Brazil | 1 | 2% |
| Unknown | 54 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 26% |
| Researcher | 13 | 23% |
| Student > Master | 5 | 9% |
| Student > Doctoral Student | 4 | 7% |
| Other | 3 | 5% |
| Other | 10 | 18% |
| Unknown | 7 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 22 | 39% |
| Agricultural and Biological Sciences | 16 | 28% |
| Medicine and Dentistry | 7 | 12% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Physics and Astronomy | 1 | 2% |
| Other | 3 | 5% |
| Unknown | 7 | 12% |