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Transgenic Zebrafish Reveal Tissue-Specific Differences in Estrogen Signaling in Response to Environmental Water Samples

Overview of attention for article published in EHP toxicogenomics journal of the National Institute of Environmental Health Sciences, January 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

news
8 news outlets
twitter
1 X user

Citations

dimensions_citation
55 Dimensions

Readers on

mendeley
89 Mendeley
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Title
Transgenic Zebrafish Reveal Tissue-Specific Differences in Estrogen Signaling in Response to Environmental Water Samples
Published in
EHP toxicogenomics journal of the National Institute of Environmental Health Sciences, January 2014
DOI 10.1289/ehp.1307329
Pubmed ID
Authors

Daniel A. Gorelick, Luke R. Iwanowicz, Alice L. Hung, Vicki S. Blazer, Marnie E. Halpern

Abstract

Environmental endocrine disruptors (EEDs) are exogenous chemicals that mimic endogenous hormones such as estrogens. Previous studies using a zebrafish transgenic reporter demonstrated that the EEDs bisphenol A and genistein preferentially activate estrogen receptors (ERs) in the larval heart compared with the liver. However, it was not known whether the transgenic zebrafish reporter was sensitive enough to detect estrogens from environmental samples, whether environmental estrogens would exhibit tissue-specific effects similar to those of BPA and genistein, or why some compounds preferentially target receptors in the heart.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 2%
United States 2 2%
Unknown 85 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 22%
Student > Ph. D. Student 15 17%
Student > Bachelor 14 16%
Researcher 13 15%
Student > Doctoral Student 4 4%
Other 12 13%
Unknown 11 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 28%
Biochemistry, Genetics and Molecular Biology 19 21%
Environmental Science 10 11%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Neuroscience 5 6%
Other 11 12%
Unknown 13 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2018.
All research outputs
#702,893
of 25,373,627 outputs
Outputs from EHP toxicogenomics journal of the National Institute of Environmental Health Sciences
#650
of 8,404 outputs
Outputs of similar age
#7,293
of 321,181 outputs
Outputs of similar age from EHP toxicogenomics journal of the National Institute of Environmental Health Sciences
#11
of 59 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,404 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,181 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.