| Title |
Antimicrobial and anti-biofilm properties of polypropylene meshes coated with metal-containing DLC thin films
|
|---|---|
| Published in |
Journal of Materials Science: Materials in Medicine, May 2017
|
| DOI | 10.1007/s10856-017-5910-y |
| Pubmed ID | |
| Authors |
Elisa M. Cazalini, Walter Miyakawa, Guilherme R. Teodoro, Argemiro S. S. Sobrinho, José E. Matieli, Marcos Massi, Cristiane Y. Koga-Ito |
| Abstract |
A promising strategy to reduce nosocomial infections related to prosthetic meshes is the prevention of microbial colonization. To this aim, prosthetic meshes coated with antimicrobial thin films are proposed. Commercial polypropylene meshes were coated with metal-containing diamond-like carbon (Me-DLC) thin films by the magnetron sputtering technique. Several dissimilar metals (silver, cobalt, indium, tungsten, tin, aluminum, chromium, zinc, manganese, tantalum, and titanium) were tested and compositional analyses of each Me-DLC were performed by Rutherford backscattering spectrometry. Antimicrobial activities of the films against five microbial species (Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis) were also investigated by a modified Kirby-Bauer test. Results showed that films containing silver and cobalt have inhibited the growth of all microbial species. Tungsten-DLC, tin-DLC, aluminum-DLC, zinc-DLC, manganese-DLC, and tantalum-DLC inhibited the growth of some strains, while chromium- and titanium-DLC weakly inhibited the growth of only one tested strain. In-DLC film showed no antimicrobial activity. The effects of tungsten-DLC and cobalt-DLC on Pseudomonas aeruginosa biofilm formation were also assessed. Tungsten-DLC was able to significantly reduce biofilm formation. Overall, the experimental results in the present study have shown new approaches to coating polymeric biomaterials aiming antimicrobial effect. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 57 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 26% |
| Researcher | 8 | 14% |
| Student > Master | 6 | 11% |
| Student > Bachelor | 4 | 7% |
| Professor | 3 | 5% |
| Other | 7 | 12% |
| Unknown | 14 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Materials Science | 15 | 26% |
| Engineering | 6 | 11% |
| Agricultural and Biological Sciences | 3 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Medicine and Dentistry | 3 | 5% |
| Other | 6 | 11% |
| Unknown | 21 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2017.
All research outputs
#14,349,470
of 22,977,819 outputs
Outputs from Journal of Materials Science: Materials in Medicine
#987
of 1,406 outputs
Outputs of similar age
#175,231
of 313,760 outputs
Outputs of similar age from Journal of Materials Science: Materials in Medicine
#6
of 14 outputs
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So far Altmetric has tracked 1,406 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
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We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.