| Title |
Why Topical Retinoids Are Mainstay of Therapy for Acne
|
|---|---|
| Published in |
Dermatology and Therapy, June 2017
|
| DOI | 10.1007/s13555-017-0185-2 |
| Pubmed ID | |
| Authors |
James Leyden, Linda Stein-Gold, Jonathan Weiss |
| Abstract |
Acne-focused dermatology expert groups have consistently recommended that most patients with acne be treated with a combination of topical retinoid and antimicrobial therapy. This is based on clinical data as well as evidence that these drug classes have different and complementary mechanisms of action that target multiple aspects of acne's complex pathophysiology. Recent evidence-based guidelines for acne, including those from the American Academy of Dermatology (AAD) and the European Dermatology Forum (EDF), have agreed that retinoids have an essential role in this widespread disease. The AAD states "retinoids are the core of topical therapy for acne because they are comedolytic, resolve the precursor microcomedone lesion, and are anti-inflammatory;" further, they "allow for maintenance of clearance." Despite uniform recommendation for use of topical retinoids, a recent study of prescribing practices from 2012 to 2014 indicated that dermatologists prescribed retinoids just 58.8% of the time while non-dermatologists prescribed them for only 32.4% of cases. In this article, we review the reasons supporting retinoids as the mainstay of acne therapy and discuss some of the perceived barriers that may be limiting use of this important drug class. Further, we discuss how and when titrating retinoid concentrations may be utilized in clinical practice. Galderma International. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| New Zealand | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 220 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 220 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 24 | 11% |
| Student > Bachelor | 22 | 10% |
| Researcher | 15 | 7% |
| Other | 13 | 6% |
| Student > Postgraduate | 12 | 5% |
| Other | 29 | 13% |
| Unknown | 105 | 48% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 41 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 29 | 13% |
| Nursing and Health Professions | 10 | 5% |
| Chemistry | 7 | 3% |
| Agricultural and Biological Sciences | 6 | 3% |
| Other | 20 | 9% |
| Unknown | 107 | 49% |
Attention Score in Context
This research output has an Altmetric Attention Score of 427. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2024.
All research outputs
#67,320
of 25,396,120 outputs
Outputs from Dermatology and Therapy
#6
of 964 outputs
Outputs of similar age
#1,491
of 331,636 outputs
Outputs of similar age from Dermatology and Therapy
#1
of 12 outputs
Altmetric has tracked 25,396,120 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 964 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.