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Interaction of molecular alterations with immune response in melanoma

Overview of attention for article published in Cancer (0008543X), May 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

news
4 news outlets
twitter
8 X users

Citations

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25 Dimensions

Readers on

mendeley
76 Mendeley
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Title
Interaction of molecular alterations with immune response in melanoma
Published in
Cancer (0008543X), May 2017
DOI 10.1002/cncr.30681
Pubmed ID
Authors

Robert A. Szczepaniak Sloane, Vancheswaran Gopalakrishnan, Sangeetha M. Reddy, Xue Zhang, Alexandre Reuben, Jennifer A. Wargo

Abstract

Major advances have been made in melanoma treatment with the use of molecularly targeted therapies and immunotherapies, and numerous regimens are now approved by the US Food and Drug Administration for patients with stage IV disease. However, therapeutic resistance remains an issue to both classes of agents, and reliable biomarkers of therapeutic response and resistance are lacking. Mechanistic insights are being gained through preclinical studies and translational research, offering potential strategies to enhance responses and survival in treated patients. A comprehensive understanding of the immune effects of common mutations at play in melanoma is critical, as is an appreciation of the molecular mechanisms contributing to therapeutic resistance to immunotherapy. These mechanisms and the interplay between them are discussed herein. Cancer 2017;123:2130-42. © 2017 American Cancer Society.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 76 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 13 17%
Researcher 11 14%
Student > Ph. D. Student 7 9%
Student > Master 5 7%
Student > Doctoral Student 4 5%
Other 12 16%
Unknown 24 32%
Readers by discipline Count As %
Medicine and Dentistry 19 25%
Biochemistry, Genetics and Molecular Biology 11 14%
Agricultural and Biological Sciences 9 12%
Immunology and Microbiology 7 9%
Nursing and Health Professions 1 1%
Other 3 4%
Unknown 26 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2017.
All research outputs
#1,296,497
of 25,728,855 outputs
Outputs from Cancer (0008543X)
#1,040
of 14,176 outputs
Outputs of similar age
#24,956
of 327,235 outputs
Outputs of similar age from Cancer (0008543X)
#42
of 176 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,176 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.5. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,235 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 176 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.