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MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expression

Overview of attention for article published in BMC Genomics, January 2014
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Title
MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expression
Published in
BMC Genomics, January 2014
DOI 10.1186/1471-2164-15-88
Pubmed ID
Authors

Santiyagu M Savarimuthu Francis, Morgan R Davidson, Maxine E Tan, Casey M Wright, Belinda E Clarke, Edwina E Duhig, Rayleen V Bowman, Nicholas K Hayward, Kwun M Fong, Ian A Yang

Abstract

MicroRNAs (MiRNA) are small non-coding RNAs that regulate gene expression. The aim of this study was to identify miRNAs differentially expressed between mild and moderately emphysematous lung, as well as their functional target mRNAs. Resected lung from patients with COPD undergoing lung cancer surgery was profiled using miRNA (Agilent Human miRNA profiler G4470 V1.01) and mRNA (OperonV2.0) microarrays. Cells of lung origin (BEAS-2B and HFL1) were profiled using mRNA microarrays (Illumina HumanHT-12 V3) after in vitro manipulation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 31%
Researcher 7 17%
Student > Master 6 14%
Student > Bachelor 4 10%
Student > Doctoral Student 1 2%
Other 4 10%
Unknown 7 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 26%
Biochemistry, Genetics and Molecular Biology 10 24%
Nursing and Health Professions 3 7%
Medicine and Dentistry 3 7%
Physics and Astronomy 2 5%
Other 4 10%
Unknown 9 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2019.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from BMC Genomics
#7,120
of 11,244 outputs
Outputs of similar age
#203,608
of 322,827 outputs
Outputs of similar age from BMC Genomics
#124
of 207 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,827 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 207 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.