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Protective Role for Toll-Like Receptor-9 in the Development of Atherosclerosis in Apolipoprotein E–Deficient Mice

Overview of attention for article published in Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire), January 2014
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Title
Protective Role for Toll-Like Receptor-9 in the Development of Atherosclerosis in Apolipoprotein E–Deficient Mice
Published in
Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire), January 2014
DOI 10.1161/atvbaha.113.302407
Pubmed ID
Authors

Christine Koulis, Yung-Chih Chen, Christian Hausding, Ingo Ahrens, Tin Soe Kyaw, Christopher Tay, Terri Allen, Karin Jandeleit-Dahm, Matthew J. Sweet, Shizuo Akira, Alexander Bobik, Karlheinz Peter, Alex Agrotis

Abstract

Atherosclerosis is driven by inflammatory reactions that are shared with the innate immune system. Toll-like receptor-9 (TLR9) is an intracellular pattern recognition receptor of the innate immune system that is currently under clinical investigation as a therapeutic target in inflammatory diseases. Here, we investigated whether TLR9 has a role in the development of atherosclerosis in apolipoprotein E-deficient (ApoE(-/-)) mice.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Netherlands 1 2%
Australia 1 2%
Unknown 57 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 20%
Researcher 10 17%
Student > Bachelor 7 12%
Student > Master 7 12%
Other 6 10%
Other 7 12%
Unknown 11 18%
Readers by discipline Count As %
Medicine and Dentistry 16 27%
Biochemistry, Genetics and Molecular Biology 11 18%
Agricultural and Biological Sciences 9 15%
Immunology and Microbiology 6 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Other 3 5%
Unknown 12 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2014.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire)
#4,887
of 6,064 outputs
Outputs of similar age
#202,012
of 319,923 outputs
Outputs of similar age from Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire)
#33
of 49 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,064 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,923 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.