Title |
Transcutaneous supraorbital neurostimulation for the prevention of chronic migraine: a prospective, open-label preliminary trial
|
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Published in |
Neurological Sciences, May 2017
|
DOI | 10.1007/s10072-017-2916-7 |
Pubmed ID | |
Authors |
Paola Di Fiore, Gennaro Bussone, Alberto Galli, Henri Didier, Cesare Peccarisi, Domenico D’Amico, Fabio Frediani |
Abstract |
Since chronic migraine is difficult to treat and often associated with medication overuse, non-invasive neurostimulation approaches are worth investigating. Transcutaneous supraorbital neurostimulation using the Cefaly(®) device is promising as a non-invasive preventive treatment for episodic migraine, but no data are available for chronic migraine. Our aim was to perform a preliminary evaluation of the efficacy of the Cefaly(®) device for the prophylaxis of chronic migraine with or without medication overuse. Primary endpoints were 50% reduction in monthly migraine days and 50% reduction in monthly medication use over 4 months. In an open-label study, twenty-three consecutive headache center patients with chronic migraine, diagnosed according to International Headache Society criteria, were recruited prospectively. After informed consent, patients were trained to use Cefaly(®) and instructed to use it for 20 min daily over 4 months. All patients received active neurostimulation. Thirty-five percent of the patients enrolled in the study achieved the study endpoints. Over half the patients had a greater than 50% reduction in acute medication consumption. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Unknown | 65 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 17% |
Other | 8 | 12% |
Student > Ph. D. Student | 8 | 12% |
Student > Bachelor | 6 | 9% |
Student > Postgraduate | 6 | 9% |
Other | 8 | 12% |
Unknown | 19 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 24% |
Neuroscience | 11 | 17% |
Nursing and Health Professions | 5 | 8% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Engineering | 3 | 5% |
Other | 8 | 12% |
Unknown | 20 | 30% |