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Therapeutic Value of Standard Versus Extended Pelvic Lymph Node Dissection During Radical Prostatectomy for High-Risk Prostate Cancer

Overview of attention for article published in Current Urology Reports, June 2017
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Title
Therapeutic Value of Standard Versus Extended Pelvic Lymph Node Dissection During Radical Prostatectomy for High-Risk Prostate Cancer
Published in
Current Urology Reports, June 2017
DOI 10.1007/s11934-017-0696-5
Pubmed ID
Authors

Michele Colicchia, Vidit Sharma, Firas Abdollah, Alberto Briganti, R. Jeffrey Karnes

Abstract

Extent of pelvic lymph node dissection (PLND) during radical prostatectomy (RP) remains a subject of debate. Here, we review the literature covering the value of extended PLND (ePLND) during RP for high-risk prostate cancer (PCa) over a standard PLND, with a focus on potential therapeutic advantage. PLND may provide valuable prognostic information to high-risk PCa patients, and incorporating the common iliac and presacral nodes to ePLND templates further improves pathologic nodal staging accuracy. Although increased PLND extent is associated with increased lymphocele/lymphedema rates, it is not associated with increased venous thromboembolism rates. The therapeutic role of ePLND remains uncertain. While recent retrospective studies suggest an increased number of nodes removed within the ePLND template are associated with improved survival outcomes, such retrospective studies cannot completely adjust for the Will Rodgers phenomenon or surgeon-specific factors. Thus, the results of randomized trials are eagerly awaited in this arena.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 19%
Student > Master 7 17%
Student > Postgraduate 5 12%
Student > Bachelor 4 10%
Student > Doctoral Student 3 7%
Other 7 17%
Unknown 8 19%
Readers by discipline Count As %
Medicine and Dentistry 25 60%
Agricultural and Biological Sciences 2 5%
Immunology and Microbiology 1 2%
Computer Science 1 2%
Unknown 13 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2018.
All research outputs
#18,554,389
of 22,979,862 outputs
Outputs from Current Urology Reports
#503
of 592 outputs
Outputs of similar age
#241,926
of 317,259 outputs
Outputs of similar age from Current Urology Reports
#12
of 22 outputs
Altmetric has tracked 22,979,862 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 592 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,259 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.