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Reversal of liver fibrosis: From fiction to reality

Overview of attention for article published in Best Practice and Research Clinical Gastroenterology, April 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

twitter
7 X users
facebook
1 Facebook page

Citations

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120 Dimensions

Readers on

mendeley
133 Mendeley
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Title
Reversal of liver fibrosis: From fiction to reality
Published in
Best Practice and Research Clinical Gastroenterology, April 2017
DOI 10.1016/j.bpg.2017.04.005
Pubmed ID
Authors

Miguel Eugenio Zoubek, Christian Trautwein, Pavel Strnad

Abstract

In chronic liver diseases, an ongoing hepatocellular injury together with inflammatory reaction results in activation of hepatic stellate cells (HSCs) and increased deposition of extracellular matrix (ECM) termed as liver fibrosis. It can progress to cirrhosis that is characterized by parenchymal and vascular architectural changes together with the presence of regenerative nodules. Even at late stage, liver fibrosis is reversible and the underlying mechanisms include a switch in the inflammatory environment, elimination or regression of activated HSCs and degradation of ECM. While animal models have been indispensable for our understanding of liver fibrosis, they possess several important limitations and need to be further refined. A better insight into the liver fibrogenesis resulted in a large number of clinical trials aiming at reversing liver fibrosis, particularly in patients with non-alcoholic steatohepatitis. Collectively, the current developments demonstrate that reversal of liver fibrosis is turning from fiction to reality.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Unknown 132 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 13%
Student > Master 17 13%
Researcher 14 11%
Student > Bachelor 12 9%
Student > Doctoral Student 11 8%
Other 21 16%
Unknown 41 31%
Readers by discipline Count As %
Medicine and Dentistry 36 27%
Biochemistry, Genetics and Molecular Biology 22 17%
Agricultural and Biological Sciences 9 7%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Unspecified 3 2%
Other 13 10%
Unknown 45 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2022.
All research outputs
#7,060,988
of 25,461,852 outputs
Outputs from Best Practice and Research Clinical Gastroenterology
#197
of 704 outputs
Outputs of similar age
#103,725
of 323,605 outputs
Outputs of similar age from Best Practice and Research Clinical Gastroenterology
#3
of 16 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 704 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,605 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.