| Title |
Hypolipidemic Activity of Cassia tora Seeds in Hyperlipidemic Rats
|
|---|---|
| Published in |
Indian Journal of Clinical Biochemistry, January 2014
|
| DOI | 10.1007/s12291-013-0412-2 |
| Pubmed ID | |
| Authors |
Vishnu Kumar Awasthi, Farzana Mahdi, Ramesh Chander, Ashok Kumar Khanna, Jitendra Kumar Saxena, Ranjana Singh, Abbas Ali Mahdi, Raj Kumar Singh |
| Abstract |
The hypolipidemic activity of Cassia tora (Chakvat, Chakunda) (Family: Caesalpiniaceae) seeds extract have been studied in two models of hyperlipidemia in rats. In an acute model, hyperlipidemia was induced by injecting a single dose of Triton WR-1339 (400 mg/kg, b.w.) intraperitonially in rats. Feeding with C. tora seed extract at the dose of 500 mg/kg, b.w. exerted significant lipid lowering effect as assessed by the reversal of plasma levels of total cholesterol, phospholipids, triglyceride and reactivation of post heparin lipolytic activity. In the chronic model, hyperlipidemia was induced by feeding with cholesterol rich-HFD in rats. The treatment with seeds extract of C. tora (500 mg/kg, b.w.) simultaneously for 15 days also caused lowering of lipid levels in plasma and liver following reactivation of plasma post heparin lipolytic activity and hepatic lipoprotein lipase activity in animals. The hypolipidemic activity of C. tora seeds was compared with a standard drug guggulipid (200 mg/kg, b.w.) in both models. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 7 | 22% |
| Student > Ph. D. Student | 6 | 19% |
| Researcher | 4 | 13% |
| Student > Master | 3 | 9% |
| Lecturer | 2 | 6% |
| Other | 2 | 6% |
| Unknown | 8 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 16% |
| Medicine and Dentistry | 5 | 16% |
| Agricultural and Biological Sciences | 3 | 9% |
| Chemistry | 3 | 9% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Other | 5 | 16% |
| Unknown | 9 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2015.
All research outputs
#14,773,697
of 22,743,667 outputs
Outputs from Indian Journal of Clinical Biochemistry
#185
of 365 outputs
Outputs of similar age
#181,947
of 306,092 outputs
Outputs of similar age from Indian Journal of Clinical Biochemistry
#1
of 5 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 365 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,092 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them