| Title |
Integrating imaging findings in evaluating the post-chemotherapy brain
|
|---|---|
| Published in |
Brain Imaging and Behavior, July 2013
|
| DOI | 10.1007/s11682-013-9239-y |
| Pubmed ID | |
| Authors |
K. L. Pomykala, M. B. de Ruiter, S. Deprez, B. C. McDonald, D. H. S. Silverman |
| Abstract |
Cognitive complaints following cancer and cancer therapy are common. Many studies have investigated the effects of chemotherapy on the brain. However, the mechanisms for the associated cognitive impairment are not well understood. Some studies have also included brain imaging to investigate potential neurological substrates of cognitive changes. This review examines recent neuroimaging studies on cancer- and chemotherapy-related cognitive dysfunction in non-central nervous system cancers and compares findings across imaging modalities. Grey matter volume reductions and decreases in white matter integrity are seen after exposure to adjuvant chemotherapy for breast cancer, and functional studies have illuminated both hypo- and hyperactivations in many of the same regions months to years following therapy. These comparisons can assist in further characterizing the dysfunction reported by patients and contribute to a better understanding of the mechanisms involved. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 71 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 21% |
| Student > Master | 11 | 15% |
| Student > Ph. D. Student | 10 | 14% |
| Student > Bachelor | 6 | 8% |
| Student > Doctoral Student | 5 | 7% |
| Other | 14 | 19% |
| Unknown | 12 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 20 | 27% |
| Medicine and Dentistry | 15 | 21% |
| Neuroscience | 8 | 11% |
| Agricultural and Biological Sciences | 5 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Other | 9 | 12% |
| Unknown | 13 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2014.
All research outputs
#18,363,356
of 22,743,667 outputs
Outputs from Brain Imaging and Behavior
#863
of 1,152 outputs
Outputs of similar age
#145,978
of 194,425 outputs
Outputs of similar age from Brain Imaging and Behavior
#10
of 15 outputs
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