Title |
Internet-based perioperative exercise program in patients with Barrett’s carcinoma scheduled for esophagectomy [iPEP - study] a prospective randomized-controlled trial
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Published in |
BMC Cancer, June 2017
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DOI | 10.1186/s12885-017-3400-8 |
Pubmed ID | |
Authors |
Daniel Pfirrmann, Suzan Tug, Oana Brosteanu, Matthias Mehdorn, Martin Busse, Peter P. Grimminger, Florian Lordick, Torben Glatz, Jens Hoeppner, Hauke Lang, Perikles Simon, Ines Gockel |
Abstract |
Patients undergoing surgery for esophageal cancer have a high risk for postoperative deterioration of lung function and pulmonary complications. This is partly due to one-lung ventilation during thoracotomy. This often accounts for prolonged stay on intensive care units, delayed postoperative reconvalescence and reduced quality of life. Socioeconomic disadvantages can result from these problems. Physical preconditioning has become a crucial leverage to optimize fitness and lung function in patients scheduled for esophagectomy, in particular during the time period of neoadjuvant therapy. We designed a prospective multicenter randomized-controlled trial. The objective is to evaluate the impact of an internet-based exercise program on postoperative respiratory parameters and pneumonia rates in patients with Barrett's carcinoma scheduled for esophagectomy. Patients are randomly assigned to either execute internet-based perioperative exercise program (iPEP), including daily endurance, resistance and ventilation training or treatment as usual (TAU). During neoadjuvant therapy and recovery, patients in the intervention group receive an individually designed intensive exercise program based on functional measurements at baseline. Personal feedback of the supervisor with customized training programs is provided in weekly intervals. This study will evaluate if an intensive individually adapted training program via online supervision during neoadjuvant therapy will improve cardiorespiratory fitness and reduce pulmonary complications following esophagectomy for Barrett's cancer. NCT02478996 , registered 26 May 2015. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 215 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 29 | 13% |
Student > Bachelor | 22 | 10% |
Researcher | 15 | 7% |
Student > Ph. D. Student | 15 | 7% |
Student > Doctoral Student | 13 | 6% |
Other | 43 | 20% |
Unknown | 78 | 36% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 42 | 20% |
Nursing and Health Professions | 35 | 16% |
Sports and Recreations | 13 | 6% |
Unspecified | 11 | 5% |
Agricultural and Biological Sciences | 4 | 2% |
Other | 24 | 11% |
Unknown | 86 | 40% |