| Title |
The microbiome-gut-brain axis: implications for schizophrenia and antipsychotic induced weight gain
|
|---|---|
| Published in |
European Archives of Psychiatry and Clinical Neuroscience, June 2017
|
| DOI | 10.1007/s00406-017-0820-z |
| Pubmed ID | |
| Authors |
S. Kanji, T. M. Fonseka, V. S. Marshe, V. Sriretnakumar, M. K. Hahn, D. J. Müller |
| Abstract |
With the emergence of knowledge implicating the human gut microbiome in the development and regulation of several physiological systems, evidence has accumulated to suggest a role for the gut microbiome in psychiatric conditions and drug response. A complex relationship between the enteric nervous system, the gut microbiota and the central nervous system has been described which allows for the microbiota to influence and respond to a variety of behaviors and psychiatric conditions. Additionally, the use of pharmaceuticals may interact with and alter the microbiota to potentially contribute to adverse effects of the drug. The gut microbiota has been described in several psychiatric disorders including depression and anxiety, but only a few reports have discussed the role of the microbiome in schizophrenia. The following review examines the evidence surrounding the gut microbiota in behavior and psychiatric illness, the role of the microbiota in schizophrenia and the potential for antipsychotics to alter the gut microbiota and promote adverse metabolic events. |
X Demographics
The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 29% |
| Italy | 1 | 7% |
| Argentina | 1 | 7% |
| Unknown | 8 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 79% |
| Practitioners (doctors, other healthcare professionals) | 2 | 14% |
| Scientists | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 217 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 217 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 43 | 20% |
| Student > Master | 33 | 15% |
| Researcher | 25 | 12% |
| Student > Ph. D. Student | 16 | 7% |
| Other | 14 | 6% |
| Other | 41 | 19% |
| Unknown | 45 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 53 | 24% |
| Biochemistry, Genetics and Molecular Biology | 22 | 10% |
| Neuroscience | 20 | 9% |
| Agricultural and Biological Sciences | 18 | 8% |
| Psychology | 10 | 5% |
| Other | 33 | 15% |
| Unknown | 61 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2019.
All research outputs
#2,611,862
of 25,654,806 outputs
Outputs from European Archives of Psychiatry and Clinical Neuroscience
#156
of 1,652 outputs
Outputs of similar age
#47,466
of 331,168 outputs
Outputs of similar age from European Archives of Psychiatry and Clinical Neuroscience
#2
of 18 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,652 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,168 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.