Title |
Characterization of Fitzroy River Virus and Serologic Evidence of Human and Animal Infection - Volume 23, Number 8—August 2017 - Emerging Infectious Diseases journal - CDC
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Published in |
Emerging Infectious Diseases, August 2017
|
DOI | 10.3201/eid2308.161440 |
Pubmed ID | |
Authors |
Cheryl A. Johansen, Simon H. Williams, Lorna F. Melville, Jay Nicholson, Roy A. Hall, Helle Bielefeldt-Ohmann, Natalie A. Prow, Glenys R. Chidlow, Shani Wong, Rohini Sinha, David T. Williams, W. Ian Lipkin, David W. Smith |
Abstract |
In northern Western Australia in 2011 and 2012, surveillance detected a novel arbovirus in mosquitoes. Genetic and phenotypic analyses confirmed that the new flavivirus, named Fitzroy River virus, is related to Sepik virus and Wesselsbron virus, in the yellow fever virus group. Most (81%) isolates came from Aedes normanensis mosquitoes, providing circumstantial evidence of the probable vector. In cell culture, Fitzroy River virus replicated in mosquito (C6/36), mammalian (Vero, PSEK, and BSR), and avian (DF-1) cells. It also infected intraperitoneally inoculated weanling mice and caused mild clinical disease in 3 intracranially inoculated mice. Specific neutralizing antibodies were detected in sentinel horses (12.6%), cattle (6.6%), and chickens (0.5%) in the Northern Territory of Australia and in a subset of humans (0.8%) from northern Western Australia. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 7 | 39% |
United Kingdom | 3 | 17% |
Nepal | 2 | 11% |
Australia | 1 | 6% |
Brazil | 1 | 6% |
Mexico | 1 | 6% |
India | 1 | 6% |
Unknown | 2 | 11% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 7 | 39% |
Members of the public | 6 | 33% |
Practitioners (doctors, other healthcare professionals) | 3 | 17% |
Science communicators (journalists, bloggers, editors) | 2 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 3 | 18% |
Student > Ph. D. Student | 3 | 18% |
Researcher | 3 | 18% |
Student > Master | 2 | 12% |
Professor | 1 | 6% |
Other | 1 | 6% |
Unknown | 4 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 24% |
Immunology and Microbiology | 3 | 18% |
Agricultural and Biological Sciences | 2 | 12% |
Biochemistry, Genetics and Molecular Biology | 2 | 12% |
Nursing and Health Professions | 1 | 6% |
Other | 1 | 6% |
Unknown | 4 | 24% |