Title |
The COMET Handbook: version 1.0
|
---|---|
Published in |
Trials, June 2017
|
DOI | 10.1186/s13063-017-1978-4 |
Pubmed ID | |
Authors |
Paula R. Williamson, Douglas G. Altman, Heather Bagley, Karen L. Barnes, Jane M. Blazeby, Sara T. Brookes, Mike Clarke, Elizabeth Gargon, Sarah Gorst, Nicola Harman, Jamie J. Kirkham, Angus McNair, Cecilia A. C. Prinsen, Jochen Schmitt, Caroline B. Terwee, Bridget Young |
Abstract |
The selection of appropriate outcomes is crucial when designing clinical trials in order to compare the effects of different interventions directly. For the findings to influence policy and practice, the outcomes need to be relevant and important to key stakeholders including patients and the public, health care professionals and others making decisions about health care. It is now widely acknowledged that insufficient attention has been paid to the choice of outcomes measured in clinical trials. Researchers are increasingly addressing this issue through the development and use of a core outcome set, an agreed standardised collection of outcomes which should be measured and reported, as a minimum, in all trials for a specific clinical area.Accumulating work in this area has identified the need for guidance on the development, implementation, evaluation and updating of core outcome sets. This Handbook, developed by the COMET Initiative, brings together current thinking and methodological research regarding those issues. We recommend a four-step process to develop a core outcome set. The aim is to update the contents of the Handbook as further research is identified. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 55 | 31% |
United States | 12 | 7% |
Australia | 9 | 5% |
Canada | 9 | 5% |
Ireland | 6 | 3% |
France | 4 | 2% |
Netherlands | 4 | 2% |
Spain | 3 | 2% |
Belgium | 3 | 2% |
Other | 17 | 10% |
Unknown | 54 | 31% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 99 | 56% |
Scientists | 45 | 26% |
Practitioners (doctors, other healthcare professionals) | 26 | 15% |
Science communicators (journalists, bloggers, editors) | 4 | 2% |
Unknown | 2 | 1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 601 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 82 | 14% |
Researcher | 78 | 13% |
Student > Master | 75 | 12% |
Student > Bachelor | 47 | 8% |
Other | 39 | 6% |
Other | 114 | 19% |
Unknown | 166 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 219 | 36% |
Nursing and Health Professions | 47 | 8% |
Social Sciences | 25 | 4% |
Psychology | 23 | 4% |
Biochemistry, Genetics and Molecular Biology | 12 | 2% |
Other | 68 | 11% |
Unknown | 207 | 34% |