Title |
Skin regeneration in three dimensions, current status, challenges and opportunities
|
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Published in |
Differentiation, June 2017
|
DOI | 10.1016/j.diff.2017.06.002 |
Pubmed ID | |
Authors |
Ahmed T. El-Serafi, Ibrahim T. El-Serafi, Moustafa Elmasry, Ingrid steinvall, Folke Sjöberg |
Abstract |
Skin regeneration is a life-saving need for many patients, whom list is stretched from burn victims to motor-car accidents. Spraying cells, either keratinocytes or stem cells, were associated with variable results and, in many cases, unfavorable outcomes. As the spatial configuration of the skin is distinctive, many trials investigated the bio-printing or the construction of three dimensional skin models where different layers of the skin were preserved. Although some of these models showed the histological configuration of the skin, their acceptance by the wound was questionable as a consequence of delayed vascularization. In this mini-review, different models for three dimensional regeneration of the skin will be discussed with their main points of strength and challenges as well as their possible opportunities. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 81 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 14 | 17% |
Student > Ph. D. Student | 11 | 14% |
Student > Master | 10 | 12% |
Researcher | 8 | 10% |
Student > Doctoral Student | 7 | 9% |
Other | 10 | 12% |
Unknown | 21 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 14 | 17% |
Medicine and Dentistry | 12 | 15% |
Engineering | 8 | 10% |
Agricultural and Biological Sciences | 7 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Other | 10 | 12% |
Unknown | 26 | 32% |