| Title |
Antihypertensive Effects of Probiotics
|
|---|---|
| Published in |
Current Hypertension Reports, March 2017
|
| DOI | 10.1007/s11906-017-0723-4 |
| Pubmed ID | |
| Authors |
Iñaki Robles-Vera, Marta Toral, Miguel Romero, Rosario Jiménez, Manuel Sánchez, Francisco Pérez-Vizcaíno, Juan Duarte |
| Abstract |
The present review focuses in the hypertension-associated changes in the microbiota and the current insights regarding the impact of probiotics on blood pressure in animal models and in human hypertensive patients. Gut dysbiosis in hypertension is characterized by (i) the gut microbioma that is less diverse and less rich with an increased Firmicutes/Bacteroidetes ratio and (ii) a decrease in acetate- and butyrate-producing bacteria and an increase in lactate-producing bacterial populations. The meta-analysis of the human studies supports that supplementation with probiotics reduces blood pressure. The mechanism of this antihypertensive effect of probiotics and its protective effect on endothelial function has not been fully elucidated. Further investigations are needed to clarify if the effects of probiotic bacteria result from the changes in the gut microbiota and its metabolic by-products; the restoration of the gut barrier function; and the effects on endotoxemia, inflammation, and renal sympathetic nerve activity. |
Mendeley readers
The data shown below were compiled from readership statistics for 157 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 157 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 25 | 16% |
| Student > Ph. D. Student | 19 | 12% |
| Student > Bachelor | 17 | 11% |
| Student > Doctoral Student | 13 | 8% |
| Researcher | 12 | 8% |
| Other | 22 | 14% |
| Unknown | 49 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 16% |
| Biochemistry, Genetics and Molecular Biology | 18 | 11% |
| Agricultural and Biological Sciences | 18 | 11% |
| Nursing and Health Professions | 10 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 6% |
| Other | 19 | 12% |
| Unknown | 57 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2019.
All research outputs
#6,856,913
of 22,982,639 outputs
Outputs from Current Hypertension Reports
#222
of 734 outputs
Outputs of similar age
#118,207
of 334,003 outputs
Outputs of similar age from Current Hypertension Reports
#12
of 25 outputs
Altmetric has tracked 22,982,639 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 734 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,003 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.