Title |
Common Genetic Variants Explain the Majority of the Correlation Between Height and Intelligence: The Generation Scotland Study
|
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Published in |
Behavior Genetics, February 2014
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DOI | 10.1007/s10519-014-9644-z |
Pubmed ID | |
Authors |
Riccardo E. Marioni, G. David Batty, Caroline Hayward, Shona M. Kerr, Archie Campbell, Lynne J. Hocking, Generation Scotland, David J. Porteous, Peter M. Visscher, Ian J. Deary |
Abstract |
Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences. |
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