| Title |
The potential of neural stem cells to repair stroke-induced brain damage
|
|---|---|
| Published in |
Acta Neuropathologica, March 2009
|
| DOI | 10.1007/s00401-009-0516-1 |
| Pubmed ID | |
| Authors |
Yi Ping Liu, Bradley T. Lang, Mustafa K. Baskaya, Robert J. Dempsey, Raghu Vemuganti |
| Abstract |
Acute injuries to CNS such as stroke induce neural progenitor proliferation in adult brain which might be an endogenous attempt to self-repair. This process is known to be altered by several exogenous and endogenous modulators including growth factors that could help to reinforce the post-stroke neurogenesis. Increasing the neurogenesis may be a future therapeutic option to decrease the cognitive and behavioral deficits following stroke. In addition, transplantation of various types of stem cells into the injured brain is currently thought to be an exciting option to replace the neurons lost in the post-ischemic brain. These include immortalized stem cell lines, neural progenitors prepared from embryonic and adult animals and mesenchymal stem cells. Using exogenous stem cells in addition to modulating endogenous neurogenesis, we may be able to repair the injured brain after a devastating stroke. This article reviewed the current literature of these two issues. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Thailand | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 2% |
| Finland | 1 | 1% |
| United States | 1 | 1% |
| Italy | 1 | 1% |
| Unknown | 82 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 23% |
| Student > Bachelor | 18 | 21% |
| Researcher | 12 | 14% |
| Student > Master | 9 | 10% |
| Student > Postgraduate | 6 | 7% |
| Other | 15 | 17% |
| Unknown | 7 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 24% |
| Agricultural and Biological Sciences | 20 | 23% |
| Neuroscience | 13 | 15% |
| Biochemistry, Genetics and Molecular Biology | 5 | 6% |
| Psychology | 5 | 6% |
| Other | 10 | 11% |
| Unknown | 13 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2017.
All research outputs
#2,221,972
of 22,745,803 outputs
Outputs from Acta Neuropathologica
#542
of 2,363 outputs
Outputs of similar age
#7,137
of 94,913 outputs
Outputs of similar age from Acta Neuropathologica
#4
of 20 outputs
Altmetric has tracked 22,745,803 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,363 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.3. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,913 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.