Title |
Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration
|
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Published in |
Journal of Clinical Biochemistry and Nutrition, June 2017
|
DOI | 10.3164/jcbn.16-87 |
Pubmed ID | |
Authors |
Kenji Dohi, Kazue Satoh, Kazuyuki Miyamoto, Shusuke Momma, Kenichiro Fukuda, Ryo Higuchi, Hirokazu Ohtaki, Williams A Banks |
Abstract |
Oxidative stress caused by reactive oxygen species is considered a major mediator of tissue and cell injuries in various neuronal conditions, including neurological emergencies and neurodegenerative diseases. Molecular hydrogen is well characterized as a scavenger of hydroxyl radicals and peroxynitrite. Recently, the neuroprotective effects of treatment with molecular hydrogen have been reported in both basic and clinical settings. Here, we review the effects of hydrogen therapy in acute neuronal conditions and neurodegenerative diseases. Hydrogen therapy administered in drinking water may be useful for the prevention of neurodegenerative diseases and for reducing the symptoms of acute neuronal conditions. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 13% |
Unknown | 7 | 88% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 88% |
Scientists | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 21% |
Student > Ph. D. Student | 3 | 16% |
Other | 2 | 11% |
Lecturer | 1 | 5% |
Professor | 1 | 5% |
Other | 3 | 16% |
Unknown | 5 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 47% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Neuroscience | 1 | 5% |
Other | 0 | 0% |
Unknown | 6 | 32% |