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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Distance to health services affects local-level vaccine efficacy for pneumococcal conjugate vaccine (PCV) among rural Filipino children
|
|---|---|
| Published in |
Proceedings of the National Academy of Sciences of the United States of America, February 2014
|
| DOI | 10.1073/pnas.1313748111 |
| Pubmed ID | |
| Authors |
Elisabeth Dowling Root, Marilla Lucero, Hanna Nohynek, Peter Anthamatten, Deborah S. K. Thomas, Veronica Tallo, Antti Tanskanen, Beatriz P. Quiambao, Taneli Puumalainen, Socorro P. Lupisan, Petri Ruutu, Erma Ladesma, Gail M. Williams, Ian Riley, Eric A. F. Simões |
| Abstract |
Pneumococcal conjugate vaccines (PCVs) have demonstrated efficacy against childhood pneumococcal disease in several regions globally. We demonstrate how spatial epidemiological analysis of a PCV trial can assist in developing vaccination strategies that target specific geographic subpopulations at greater risk for pneumococcal pneumonia. We conducted a secondary analysis of a randomized, placebo-controlled, double-blind vaccine trial that examined the efficacy of an 11-valent PCV among children less than 2 y of age in Bohol, Philippines. Trial data were linked to the residential location of each participant using a geographic information system. We use spatial interpolation methods to create smoothed surface maps of vaccination rates and local-level vaccine efficacy across the study area. We then measure the relationship between distance to the main study hospital and local-level vaccine efficacy, controlling for ecological factors, using spatial autoregressive models with spatial autoregressive disturbances. We find a significant amount of spatial variation in vaccination rates across the study area. For the primary study endpoint vaccine efficacy increased with distance from the main study hospital from -14% for children living less than 1.5 km from Bohol Regional Hospital (BRH) to 55% for children living greater than 8.5 km from BRH. Spatial regression models indicated that after adjustment for ecological factors, distance to the main study hospital was positively related to vaccine efficacy, increasing at a rate of 4.5% per kilometer distance. Because areas with poor access to care have significantly higher VE, targeted vaccination of children in these areas might allow for a more effective implementation of global programs. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| Peru | 1 | <1% |
| Nigeria | 1 | <1% |
| China | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 119 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 24 | 19% |
| Student > Master | 20 | 16% |
| Student > Ph. D. Student | 19 | 15% |
| Student > Bachelor | 9 | 7% |
| Student > Doctoral Student | 8 | 6% |
| Other | 21 | 17% |
| Unknown | 24 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 34 | 27% |
| Social Sciences | 13 | 10% |
| Agricultural and Biological Sciences | 11 | 9% |
| Nursing and Health Professions | 8 | 6% |
| Psychology | 6 | 5% |
| Other | 24 | 19% |
| Unknown | 29 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2014.
All research outputs
#4,195,496
of 24,625,114 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#42,537
of 101,438 outputs
Outputs of similar age
#39,793
of 229,501 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#508
of 1,002 outputs
Altmetric has tracked 24,625,114 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 101,438 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.8. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,501 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 1,002 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.