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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Severe hidradenitis suppurativa responding to treatment with secukinumab: a case report
|
|---|---|
| Published in |
British Journal of Dermatology, March 2018
|
| DOI | 10.1111/bjd.15769 |
| Pubmed ID | |
| Authors |
L. Thorlacius, P. Theut Riis, G.B.E. Jemec |
| Abstract |
An inappropriate immunologic response to an unknown antigen has been suggested to play a role in the pathogenesis of Hidradenitis suppurativa (HS). Studies have identified elevated levels of several proinflammatory cytokines, including IL-17A and TNF-α, nominating these as possible therapeutic targets.(1) Secukinumab is an Il-17A monoclonal antibody, which binds to Il-17A and inhibits the cytokine interaction with the Il-17 receptors, inhibiting the inflammatory cascade. Here we report on a case of a 47-year-old man, with Hurley Stage III lesions at the neck, axillae, breasts, genital skin and buttocks, who had experienced only temporary benefit from different medical treatments over the years. After 12 weeks of treatment with secukinumab the number of lesions reported reported by the patient within the period of the last 4 weeks was reduced from 23 to 7, pain VAS was reduced from 5 to 3 and pain/utility/handicap VAS was reduced from 7 to 4. The results may be taken to imply that IL-17 blockade could provide a possible therapeutic approach in HS. This article is protected by copyright. All rights reserved. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 17% |
| Australia | 2 | 17% |
| France | 1 | 8% |
| Ireland | 1 | 8% |
| Unknown | 6 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 83% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
| Scientists | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 56 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 7 | 13% |
| Student > Ph. D. Student | 6 | 11% |
| Student > Doctoral Student | 5 | 9% |
| Researcher | 4 | 7% |
| Student > Postgraduate | 4 | 7% |
| Other | 7 | 13% |
| Unknown | 23 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 46% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Computer Science | 1 | 2% |
| Immunology and Microbiology | 1 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Other | 4 | 7% |
| Unknown | 21 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2022.
All research outputs
#3,374,957
of 25,382,440 outputs
Outputs from British Journal of Dermatology
#1,237
of 9,663 outputs
Outputs of similar age
#67,115
of 346,396 outputs
Outputs of similar age from British Journal of Dermatology
#33
of 264 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,663 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 346,396 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 264 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.