Title |
Differences in Neural Correlates of Speech Perception in 3 Month Olds at High and Low Risk for Autism Spectrum Disorder
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Published in |
Journal of Autism and Developmental Disorders, July 2017
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DOI | 10.1007/s10803-017-3222-1 |
Pubmed ID | |
Authors |
Laura A. Edwards, Jennifer B. Wagner, Helen Tager-Flusberg, Charles A. Nelson |
Abstract |
In this study, we investigated neural precursors of language acquisition as potential endophenotypes of autism spectrum disorder (ASD) in 3-month-old infants at high and low familial ASD risk. Infants were imaged using functional near-infrared spectroscopy while they listened to auditory stimuli containing syllable repetitions; their neural responses were analyzed over left and right temporal regions. While female low risk infants showed initial neural activation that decreased over exposure to repetition-based stimuli, potentially indicating a habituation response to repetition in speech, female high risk infants showed no changes in neural activity over exposure. This finding may indicate a potential neural endophenotype of language development or ASD specific to females at risk for the disorder. |
X Demographics
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United States | 3 | 50% |
Unknown | 3 | 50% |
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Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
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Student > Ph. D. Student | 22 | 23% |
Student > Master | 16 | 17% |
Student > Bachelor | 14 | 15% |
Researcher | 12 | 13% |
Student > Doctoral Student | 6 | 6% |
Other | 9 | 9% |
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Neuroscience | 7 | 7% |
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Other | 11 | 12% |
Unknown | 21 | 22% |