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Molecular aspects of diabetes mellitus: Resistin, microRNA, and exosome

Overview of attention for article published in Journal of Cellular Biochemistry, August 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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1 patent

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97 Dimensions

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102 Mendeley
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Title
Molecular aspects of diabetes mellitus: Resistin, microRNA, and exosome
Published in
Journal of Cellular Biochemistry, August 2017
DOI 10.1002/jcb.26271
Pubmed ID
Authors

Mohammad Javad Saeedi Borujeni, Ebrahim Esfandiary, Gholamreza Taheripak, Pilar Codoñer‐Franch, Eulalia Alonso‐Iglesias, Hamed Mirzaei

Abstract

Diabetes mellitus (DM) is known as one of important common endocrine disorders which could due to deregulation of a variety of cellular and molecular pathways. A large numbers studies indicated that various pathogenesis events including mutation, serin phosphorylation and increasing/decreasing expression of many genes could contribute to initiation and progression of DM. Insulin resistance is one of important factors which could play critical roles in DM pathogenesis. It has been showed that insulin resistance via targeting a sequence of cellular and molecular pathways (e.g. PI3 kinases, PPARγ co-activator-1, microRNAs, serine/threonine kinase Akt, and serin phosphorylation) could induce DM. Among of various factors involved in DM pathogenesis, microRNAs and exosomes have been emerged as effective factors in initiation and progression of DM. A variety of studies indicated that deregulation of these molecules could change behavior of various types of cells and contribute to progression of DM. Resistin is other main factor which is known as signal molecule involved in insulin resistance. Multiple lines evidence indicated that resistin exerts its effects via affecting on glucose metabolism, inhibition of fatty acid uptake and metabolism with affecting on a variety of targets such as CD36, fatty acid transport protein 1, Acetyl-CoA carboxylase, and AMP-activated protein kinase. Here, we summarized various molecular aspects are associated with DM particularly the molecular pathways involved in insulin resistance and resistin in DM. Moreover, we highlighted exosomes and microRNAs as effective players in initiation and progression of DM. This article is protected by copyright. All rights reserved.

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X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 102 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 20 20%
Student > Ph. D. Student 16 16%
Researcher 12 12%
Student > Master 6 6%
Student > Doctoral Student 5 5%
Other 13 13%
Unknown 30 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 24 24%
Medicine and Dentistry 19 19%
Agricultural and Biological Sciences 9 9%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Nursing and Health Professions 2 2%
Other 12 12%
Unknown 32 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2022.
All research outputs
#5,973,668
of 24,406,515 outputs
Outputs from Journal of Cellular Biochemistry
#823
of 4,797 outputs
Outputs of similar age
#88,015
of 321,211 outputs
Outputs of similar age from Journal of Cellular Biochemistry
#12
of 93 outputs
Altmetric has tracked 24,406,515 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,797 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,211 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.