Title |
Vitamin D, glucose tolerance and insulinaemia in elderly men
|
---|---|
Published in |
Diabetologia, February 1997
|
DOI | 10.1007/s001250050685 |
Pubmed ID | |
Authors |
K. C. R. Baynes, B. J. Boucher, E. J. M. Feskens, D. Kromhout |
Abstract |
Vitamin D status was assessed in 142 elderly Dutchmen participating in a prospective population-based study of environmental factors in the aetiology of non-insulin-dependent diabetes mellitus. Of the men aged 70-88 years examined between March and May 1990, 39% were vitamin D depleted. After adjustment for confounding by age, BMI, physical activity, month of sampling, cigarette smoking and alcohol intake the 1-h glucose and area under the glucose curve during a standard 75-g oral glucose tolerance test (OGTT) were inversely associated with the serum concentration of 25-OH vitamin D (r = -0.23, p < 0.01; r = -0.26, p < 0.01, respectively). After excluding newly diagnosed diabetic patients total insulin concentrations during OGTT were also inversely associated with the concentration of 25-OH vitamin D (r = -0.18 to -0.23, p < 0.05). Hypovitaminosis D may be a significant risk factor for glucose intolerance. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 3% |
United Kingdom | 1 | 1% |
Italy | 1 | 1% |
Canada | 1 | 1% |
Unknown | 71 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 16% |
Researcher | 11 | 14% |
Student > Bachelor | 11 | 14% |
Professor > Associate Professor | 7 | 9% |
Student > Ph. D. Student | 6 | 8% |
Other | 19 | 25% |
Unknown | 10 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 30% |
Agricultural and Biological Sciences | 13 | 17% |
Biochemistry, Genetics and Molecular Biology | 9 | 12% |
Nursing and Health Professions | 6 | 8% |
Sports and Recreations | 3 | 4% |
Other | 6 | 8% |
Unknown | 16 | 21% |