| Title |
Multicenter, cross-sectional observational study of the impact of neuropathic pain on quality of life in cancer patients
|
|---|---|
| Published in |
Supportive Care in Cancer, July 2017
|
| DOI | 10.1007/s00520-017-3806-5 |
| Pubmed ID | |
| Authors |
So Yeon Oh, Sang Won Shin, Su-Jin Koh, Sang Byung Bae, Hyun Chang, Jung Han Kim, Hyo Jung Kim, Young Seon Hong, Keon Uk Park, Jeanno Park, Kyung Hee Lee, Na Ri Lee, Jung Lim Lee, Joung Soon Jang, Dae Sik Hong, Seung-Sei Lee, Sun Kyung Baek, Dae Ro Choi, Jooseop Chung, Sang Cheul Oh, Hye Sook Han, Hwan Jung Yun, Sun Jin Sym, So Young Yoon, In Sil Choi, Byoung Yong Shim, Seok Yun Kang, Sung Rok Kim, Hyun Joo Kim |
| Abstract |
Neuropathic cancer pain (NCP) is a common and potentially debilitating symptom in cancer patients. We investigated the prevalence of NCP, as well as its management and association with QOL. Cancer patients with pain ≥1 on the visual analogue scale (VAS) were surveyed with the Douleur Neuropathique (DN4) questionnaire, the Brief Pain Inventory-Short Form (BPI-SF), and the EuroQOL five dimensions (EQ-5D) questionnaire. The associations between NCP and pain severity or NCP and QOL, while controlling for variables relevant to QOL, were then analyzed. A total of 2003 patients were enrolled in this survey; the prevalence of NCP was 36.0% (n = 722, 95% CI, 32.5-39.5). We found that NCP in cancer patients was closely correlated to a higher pain severity (BPI-SF; 4.96 ± 1.94 versus 4.24 ± 2.02, p < 0.001), and in patients with NCP, pain more severely interfered with daily living, as compared to those without NCP (BPI-SF; 4.86 ± 2.71 versus 4.41 ± 2.87, p < 0.001). Patients with NCP also had worse QOL than those without NCP, as measured by EQ-5D index score (0.47 ± 0.30 vs. 0.51 ± 0.30, p = 0.005), and this was confirmed using multivariate analysis (p < 0.001), even after controlling for other variables such as age, sex, disease stage, cancer duration, radiotherapy, chemotherapy, and comorbidities. Importantly, adjuvant analgesics were used in less than half of patients with NCP (n = 358, 46.4%). We found that NCP in cancer patients was significantly associated with a worsened QOL, and current management is inadequate. Therefore, future research aimed at developing improved strategies for management of NCP is required. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 60 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 9 | 15% |
| Student > Master | 7 | 12% |
| Researcher | 5 | 8% |
| Other | 5 | 8% |
| Student > Doctoral Student | 4 | 7% |
| Other | 10 | 17% |
| Unknown | 20 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 22% |
| Nursing and Health Professions | 11 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Social Sciences | 2 | 3% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 7 | 12% |
| Unknown | 23 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2018.
All research outputs
#2,800,227
of 22,986,950 outputs
Outputs from Supportive Care in Cancer
#548
of 4,637 outputs
Outputs of similar age
#53,361
of 312,623 outputs
Outputs of similar age from Supportive Care in Cancer
#16
of 72 outputs
Altmetric has tracked 22,986,950 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,637 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 87% of its peers.
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We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.