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Scleral wound healing with cross-link technique using riboflavin and ultraviolet A on rabbit eyes

Overview of attention for article published in Clinical Ophthalmology, July 2017
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Title
Scleral wound healing with cross-link technique using riboflavin and ultraviolet A on rabbit eyes
Published in
Clinical Ophthalmology, July 2017
DOI 10.2147/opth.s139657
Pubmed ID
Authors

Nadyr A Damasceno, Nadia C Miguel, Marcelo Palis Ventura, Miguel Burnier, Marcos P Avila, Eduardo F Damasceno

Abstract

The aim of study was to evaluate the cross-link using riboflavin and ultraviolet A (UVA) for improving scleral wound healing. This was an experimental study involving four New Zealand rabbits (eight eyes). Therapy procedure was chosen for the right eye and control procedure for the left one. UVA irradiation of 365 nm with a surface irradiance of 3 mW/cm(2) and a photosensitizer of riboflavin drops were applied for 30 minutes on the right eye at 2 mm from the limbus. Sclerotomy incision was performed at 2 mm from the limbus in both right (on the cross-link-treated area) and left eye. Then, 30 days after surgery, a morphological analysis and histological staining with hematoxylin-eosin and picrosirius red were performed, and the sclerotomy cicatrization of right and left eyes was compared. The variables investigated were as follows: sclerotomy incision pictures and measurements were made using the ImageJ Software. Scleral thickness was measured (employing the anterior optical coherence tomography and the digital caliper). Collagen fiber density stained with picrosirius red staining was measured using the Image Pro Plus software. The morphological analysis showed that in all samples, the right eye presented sclerotomy closure, and in two eyes, among them, there were no visible edges of the sclerotomies incision. The left eye presented sclerotomy closure and incision edges. The Image Pro demonstrated a higher density of collagen fibers in the right eye when compared to the one. The statistical analysis was significant when compared to the collagen fiber density in the treated eyes with the control eyes. The cross-link procedure resulted in a better sclerotomy wound healing.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 15%
Professor > Associate Professor 3 15%
Student > Master 2 10%
Student > Ph. D. Student 1 5%
Lecturer > Senior Lecturer 1 5%
Other 2 10%
Unknown 8 40%
Readers by discipline Count As %
Medicine and Dentistry 8 40%
Chemistry 2 10%
Neuroscience 1 5%
Social Sciences 1 5%
Unknown 8 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2017.
All research outputs
#16,051,091
of 25,382,440 outputs
Outputs from Clinical Ophthalmology
#1,345
of 3,714 outputs
Outputs of similar age
#186,278
of 326,871 outputs
Outputs of similar age from Clinical Ophthalmology
#19
of 35 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,714 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,871 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.