| Title |
Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia
|
|---|---|
| Published in |
Journal of Neuroinflammation, February 2013
|
| DOI | 10.1186/1742-2094-10-23 |
| Pubmed ID | |
| Authors |
Linli Yao, Enci Mary Kan, Jia Lu, Aijun Hao, S Thameem Dheen, Charanjit Kaur, Eng-Ang Ling |
| Abstract |
Hypoxia induces microglial activation which causes damage to the developing brain. Microglia derived inflammatory mediators may contribute to this process. Toll-like receptor 4 (TLR4) has been reported to induce microglial activation and cytokines production in brain injuries; however, its role in hypoxic injury remains uncertain. We investigate here TLR4 expression and its roles in neuroinflammation in neonatal rats following hypoxic injury. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 246 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| United Kingdom | 1 | <1% |
| Poland | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 241 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 51 | 21% |
| Researcher | 36 | 15% |
| Student > Master | 35 | 14% |
| Student > Bachelor | 29 | 12% |
| Student > Doctoral Student | 17 | 7% |
| Other | 34 | 14% |
| Unknown | 44 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 55 | 22% |
| Neuroscience | 44 | 18% |
| Medicine and Dentistry | 36 | 15% |
| Biochemistry, Genetics and Molecular Biology | 30 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 6% |
| Other | 17 | 7% |
| Unknown | 50 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2022.
All research outputs
#17,365,807
of 25,483,400 outputs
Outputs from Journal of Neuroinflammation
#2,027
of 2,951 outputs
Outputs of similar age
#194,363
of 291,629 outputs
Outputs of similar age from Journal of Neuroinflammation
#19
of 33 outputs
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