Title |
Microsatellite Mutation Rate in Atlantic Sturgeon (Acipenser oxyrinchus).
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Published in |
Journal of Heredity, July 2017
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DOI | 10.1093/jhered/esx057 |
Pubmed ID | |
Authors |
Hanna Panagiotopoulou, James D Austin, Katarzyna Zalewska, Magdalena Gonciarz, Kinga Czarnogórska, Jan Gawor, Piotr Weglenski, Danijela Popovic |
Abstract |
Understanding mutation rates can greatly extend the utility of population and conservation genetic analyses. Herein, we present an estimate of genome-wide microsatellite mutation rate in Atlantic sturgeon (Acipenser oxyrinchus) based on parent-offspring transmission patterns. We screened 307 individuals for parentage and mutation-rate analysis applying 43 variable markers. Out of 13228 allele transfers, 11 mutations were detected, producing a mutation rate of 8.3 × 10-4 per locus per generation (95% confidence interval: 1.48 × 10-3, 4.15 × 10-4). Single-step mutations predominated and there were trends toward mutations in loci with greater polymorphism and allele length. Two of the detected mutations were most probably cluster mutations, being identified in 12 and 28 sibs, respectively. Finally, we observed evidences of polyploidy based on the sporadic presence of 3 or 4 alleles per locus in the genotyped individuals, supporting previous reports of incomplete diploidization in Atlantic sturgeon. |
X Demographics
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Unknown | 2 | 100% |
Demographic breakdown
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 50% |
Student > Ph. D. Student | 5 | 28% |
Student > Doctoral Student | 1 | 6% |
Student > Master | 1 | 6% |
Professor > Associate Professor | 1 | 6% |
Other | 0 | 0% |
Unknown | 1 | 6% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 9 | 50% |
Biochemistry, Genetics and Molecular Biology | 5 | 28% |
Environmental Science | 2 | 11% |
Unknown | 2 | 11% |