Title |
Protein differences between human trapezius and vastus lateralis muscles determined with a proteomic approach
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Published in |
BMC Musculoskeletal Disorders, August 2011
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DOI | 10.1186/1471-2474-12-181 |
Pubmed ID | |
Authors |
Jenny Hadrévi, Fredrik Hellström, Thomas Kieselbach, Christer Malm, Fatima Pedrosa-Domellöf |
Abstract |
The trapezius muscle is a neck muscle that is susceptible to chronic pain conditions associated with repetitive tasks, commonly referred to as chronic work-related myalgia, hence making the trapezius a muscle of clinical interest. To provide a basis for further investigations of the proteomic traits of the trapezius muscle in disease, two-dimensional difference gel electrophoresis (2D-DIGE) was performed on the healthy trapezius using vastus lateralis as a reference. To obtain as much information as possible from the vast proteomic data set, both one-way ANOVA, with and without false discovery rate (FDR) correlation, and partial least square projection to latent structures with discriminant analysis (PLS-DA) were combined to compare the outcome of the analysis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 3 | 20% |
Student > Bachelor | 2 | 13% |
Student > Master | 2 | 13% |
Professor | 2 | 13% |
Unspecified | 1 | 7% |
Other | 2 | 13% |
Unknown | 3 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 4 | 27% |
Agricultural and Biological Sciences | 2 | 13% |
Unspecified | 1 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Nursing and Health Professions | 1 | 7% |
Other | 2 | 13% |
Unknown | 4 | 27% |