| Title |
Calcium signalling and psychiatric disease: bipolar disorder and schizophrenia
|
|---|---|
| Published in |
Cell and Tissue Research, February 2014
|
| DOI | 10.1007/s00441-014-1806-z |
| Pubmed ID | |
| Authors |
Michael J. Berridge |
| Abstract |
Neurons have highly developed Ca(2+) signalling systems responsible for regulating many neural functions such as the generation of brain rhythms, information processing and the changes in synaptic plasticity that underpins learning and memory. The signalling mechanisms that regulate neuronal excitability are particularly important for processes such as sensory perception, cognition and consciousness. The Ca(2+) signalling pathway is a key component of the mechanisms responsible for regulating neuronal excitability, information processing and cognition. Alterations in gene transcription are particularly important as they result in subtle alterations in the neuronal signalling mechanisms that have been implicated in many neural diseases. In particular, dysregulation of the Ca(2+) signalling pathway has been implicated in the development of some of the major psychiatric diseases such as bipolar disorder (BPD) and schizophrenia. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 190 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| United States | 1 | <1% |
| Peru | 1 | <1% |
| Unknown | 186 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 21% |
| Student > Bachelor | 31 | 16% |
| Student > Master | 26 | 14% |
| Researcher | 22 | 12% |
| Student > Doctoral Student | 9 | 5% |
| Other | 27 | 14% |
| Unknown | 36 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 40 | 21% |
| Neuroscience | 29 | 15% |
| Medicine and Dentistry | 22 | 12% |
| Biochemistry, Genetics and Molecular Biology | 20 | 11% |
| Psychology | 13 | 7% |
| Other | 20 | 11% |
| Unknown | 46 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2024.
All research outputs
#1,631,627
of 23,839,820 outputs
Outputs from Cell and Tissue Research
#18
of 2,279 outputs
Outputs of similar age
#16,880
of 223,075 outputs
Outputs of similar age from Cell and Tissue Research
#1
of 31 outputs
Altmetric has tracked 23,839,820 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,279 research outputs from this source. They receive a mean Attention Score of 3.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 223,075 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.