| Title |
Potent Anticoagulants are Associated with a Higher All‐Cause Mortality Rate After Hip and Knee Arthroplasty
|
|---|---|
| Published in |
Clinical Orthopaedics & Related Research, February 2008
|
| DOI | 10.1007/s11999-007-0092-4 |
| Pubmed ID | |
| Authors |
Nigel E. Sharrock, Alejandro Gonzalez Della Valle, George Go, Stephen Lyman, Eduardo A. Salvati |
| Abstract |
Anticoagulation for thromboprophylaxis after THA and TKA has not been confirmed to diminish all-cause mortality. We determined whether the incidence of all-cause mortality and pulmonary embolism in patients undergoing total joint arthroplasty differs with currently used thromboprophylaxis protocols. We reviewed articles published from 1998 to 2007 that included 6-week or 3-month incidence of all-cause mortality and symptomatic, nonfatal pulmonary embolism. Twenty studies included reported 15,839 patients receiving low-molecular-weight heparin, ximelagatran, fondaparinux, or rivaroxaban (Group A); 7193 receiving regional anesthesia, pneumatic compression, and aspirin (Group B); and 5006 receiving warfarin (Group C). All-cause mortality was higher in Group A than in Group B (0.41% versus 0.19%) and the incidence of clinical nonfatal pulmonary embolus was higher in Group A than in Group B (0.60% versus 0.35%). The incidences of all-cause mortality and nonfatal pulmonary embolism in Group C were similar to those in Group A (0.4 and 0.52, respectively). Clinical pulmonary embolus occurs despite the use of anticoagulants. Group A anticoagulants were associated with the highest all-cause mortality of the three modalities studied. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Korea, Republic of | 1 | <1% |
| South Africa | 1 | <1% |
| Ukraine | 1 | <1% |
| Canada | 1 | <1% |
| Slovenia | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 114 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 22 | 18% |
| Researcher | 15 | 13% |
| Student > Bachelor | 12 | 10% |
| Professor > Associate Professor | 10 | 8% |
| Student > Ph. D. Student | 8 | 7% |
| Other | 38 | 32% |
| Unknown | 15 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 83 | 69% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Agricultural and Biological Sciences | 2 | 2% |
| Nursing and Health Professions | 2 | 2% |
| Unspecified | 2 | 2% |
| Other | 5 | 4% |
| Unknown | 23 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2012.
All research outputs
#4,607,456
of 25,373,627 outputs
Outputs from Clinical Orthopaedics & Related Research
#986
of 7,298 outputs
Outputs of similar age
#21,708
of 174,043 outputs
Outputs of similar age from Clinical Orthopaedics & Related Research
#13
of 59 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,298 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,043 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.