Title |
Tobacco Harm Reduction with Vaporised Nicotine (THRiVe): The Study Protocol of an Uncontrolled Feasibility Study of Novel Nicotine Replacement Products among People Living with HIV Who Smoke
|
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Published in |
International Journal of Environmental Research and Public Health, July 2017
|
DOI | 10.3390/ijerph14070799 |
Pubmed ID | |
Authors |
Stephanie Bell, Judith Dean, Charles Gilks, Mark A. Boyd, Lisa Fitzgerald, Allyson Mutch, Peter Baker, Graham Neilsen, Coral E. Gartner |
Abstract |
Smoking is a leading cause of morbidity and premature mortality among people living with HIV (PLHIV), who have high rates of tobacco smoking. Vaporised nicotine products (VNPs) are growing in popularity as a quit aid and harm reduction tool. However, little is known about their acceptability and use among PLHIV. Using a pragmatic, uncontrolled, mixed methods design this exploratory clinical trial aims to examine the feasibility of conducting a powered randomised clinical trial of VNPs as a smoking cessation and harm reduction intervention among vulnerable populations, such as PLHIV who smoke tobacco. Convenience sampling and snowball methods will be used to recruit participants (N = 30) who will receive two VNPs and up to 12 weeks' supply of nicotine e-liquid to use in a quit attempt. Surveys will be completed at weeks 0 (baseline), 4, 8, 12 (end of treatment) and 24 (end of the study) and qualitative interviews at weeks 0 and 12. As far as we are aware, this feasibility study is the first to trial VNPs among PLHIV for smoking cessation. If feasible and effective, this intervention could offer a new approach to reducing the high burden of tobacco-related disease among PLHIV and other vulnerable populations. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 3 | 60% |
Switzerland | 1 | 20% |
New Zealand | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 60% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 79 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 13 | 16% |
Researcher | 10 | 13% |
Student > Ph. D. Student | 6 | 8% |
Professor | 5 | 6% |
Student > Bachelor | 5 | 6% |
Other | 13 | 16% |
Unknown | 27 | 34% |
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Medicine and Dentistry | 18 | 23% |
Nursing and Health Professions | 10 | 13% |
Psychology | 7 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Social Sciences | 2 | 3% |
Other | 9 | 11% |
Unknown | 30 | 38% |