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Rapid nucleic acid diagnostics for the detection of antimicrobial resistance in Gram-negative bacteria: is it time for a paradigm shift?

Overview of attention for article published in Journal of Antimicrobial Chemotherapy (JAC), March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

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8 X users
patent
1 patent

Citations

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43 Dimensions

Readers on

mendeley
127 Mendeley
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Title
Rapid nucleic acid diagnostics for the detection of antimicrobial resistance in Gram-negative bacteria: is it time for a paradigm shift?
Published in
Journal of Antimicrobial Chemotherapy (JAC), March 2014
DOI 10.1093/jac/dku083
Pubmed ID
Authors

Nina Tuite, Kate Reddington, Thomas Barry, Alimuddin Zumla, Virve Enne

Abstract

A key component for tackling the ever more serious antimicrobial resistance problem in Gram-negative bacteria is the introduction of rapid nucleic acid diagnostics. Successful incorporation of new diagnostic technologies has the potential benefit of improving not only patient treatment but also infection control and antimicrobial stewardship. However, there are still many hurdles to overcome, such as the complexity of resistance mechanisms in Gram-negative bacteria, the discrepancy between phenotype and genotype and the difficulty in distinguishing pathogens from background commensals. A small number of manufacturers have introduced tests to the market that concentrate partly or specifically on resistance determinants in Gram-negative bacteria. These are currently predominantly based on different types of PCR technology. The development of new technologies, such as whole-genome sequencing and the combination of MALDI-TOF with PCR, holds much promise for the introduction of improved diagnostics for the future.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Unknown 125 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 26 20%
Student > Ph. D. Student 15 12%
Other 13 10%
Student > Master 11 9%
Student > Bachelor 11 9%
Other 28 22%
Unknown 23 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 18%
Medicine and Dentistry 22 17%
Biochemistry, Genetics and Molecular Biology 15 12%
Immunology and Microbiology 14 11%
Engineering 9 7%
Other 18 14%
Unknown 26 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2023.
All research outputs
#4,696,379
of 25,728,855 outputs
Outputs from Journal of Antimicrobial Chemotherapy (JAC)
#1,826
of 8,224 outputs
Outputs of similar age
#43,205
of 238,832 outputs
Outputs of similar age from Journal of Antimicrobial Chemotherapy (JAC)
#24
of 102 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,224 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,832 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 102 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.