Title |
Hypermethylation in the ZBTB20 gene is associated with major depressive disorder
|
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Published in |
Genome Biology, April 2014
|
DOI | 10.1186/gb-2014-15-4-r56 |
Pubmed ID | |
Authors |
Matthew N Davies, Lutz Krause, Jordana T Bell, Fei Gao, Kirsten J Ward, Honglong Wu, Hanlin Lu, Yuan Liu, Pei-Chein Tsai, David A Collier, Therese Murphy, Emma Dempster, Jonathan Mill, UK Brain Expression Consortium, Alexis Battle, Sara Mostafavi, Xiaowei Zhu, Anjali Henders, Enda Byrne, Naomi R Wray, Nicholas G Martin, Tim D Spector, Jun Wang |
Abstract |
Although genetic variation is believed to contribute to an individual's susceptibility to major depressive disorder, genome-wide association studies have not yet identified associations that could explain the full etiology of the disease. Epigenetics is increasingly believed to play a major role in the development of common clinical phenotypes, including major depressive disorder. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 7 | 21% |
United Kingdom | 6 | 18% |
Spain | 2 | 6% |
Canada | 1 | 3% |
Ireland | 1 | 3% |
Switzerland | 1 | 3% |
Belgium | 1 | 3% |
Germany | 1 | 3% |
Argentina | 1 | 3% |
Other | 1 | 3% |
Unknown | 12 | 35% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 18 | 53% |
Scientists | 12 | 35% |
Science communicators (journalists, bloggers, editors) | 2 | 6% |
Practitioners (doctors, other healthcare professionals) | 2 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 1% |
Luxembourg | 1 | <1% |
Canada | 1 | <1% |
Unknown | 134 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 21 | 15% |
Student > Ph. D. Student | 20 | 14% |
Student > Master | 17 | 12% |
Researcher | 15 | 11% |
Student > Postgraduate | 8 | 6% |
Other | 21 | 15% |
Unknown | 36 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 33 | 24% |
Biochemistry, Genetics and Molecular Biology | 24 | 17% |
Medicine and Dentistry | 16 | 12% |
Psychology | 9 | 7% |
Neuroscience | 8 | 6% |
Other | 9 | 7% |
Unknown | 39 | 28% |