Title |
Scalp eschar and neck lymphadenopathy after tick bite: an emerging syndrome with multiple causes
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Published in |
European Journal of Clinical Microbiology & Infectious Diseases, March 2014
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DOI | 10.1007/s10096-014-2090-2 |
Pubmed ID | |
Authors |
G. Dubourg, C. Socolovschi, P. Del Giudice, P. E. Fournier, D. Raoult |
Abstract |
The clinical and epidemiological features of 56 patients with scalp eschar associated with neck lymphadenopathy after a tick bite (SENLAT) syndrome were evaluated at the National French Rickettsial Center. Eschar swabs, crusts, and biopsies as well as ticks and blood samples were acquired for molecular and serological assays. SENLAT predominantly affects children (p < 0.05), followed by 40- to 70-year-olds, and it is found mostly in women (p < 0.05). The seasonal distribution has two peaks: one in the spring (55%) and one in the autumn (30%). The etiological agent was identified in 18 cases, which include Rickettsia slovaca in 13 cases with incidences of two co-infections with Rickettsia raoultii and one case caused by Rickettsia sibirica mongolitimonae. Other possible agents that were found in attached ticks were Candidatus R. rioja, Coxiella burnetii, and Borrelia burgdorferi. The tick vector was Dermacentor marginatus in almost all cases, with the exception of one case, in which Ixodes ricinus was identified as the vector. Our findings show that SENLAT is a clinical entity characterized as a local infection controlled by the immune system and is neither pathogen- nor vector-specific. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 4% |
Japan | 1 | 2% |
Unknown | 44 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 26% |
Student > Master | 6 | 13% |
Student > Doctoral Student | 6 | 13% |
Student > Ph. D. Student | 5 | 11% |
Student > Postgraduate | 3 | 6% |
Other | 8 | 17% |
Unknown | 7 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 30% |
Agricultural and Biological Sciences | 6 | 13% |
Veterinary Science and Veterinary Medicine | 5 | 11% |
Immunology and Microbiology | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Other | 3 | 6% |
Unknown | 12 | 26% |