↓ Skip to main content

Association of dopamine receptor gene polymorphism and psychological personality traits in liability for opioid addiction

Overview of attention for article published in Biomolecules and Biomedicine, August 2013
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
36 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Association of dopamine receptor gene polymorphism and psychological personality traits in liability for opioid addiction
Published in
Biomolecules and Biomedicine, August 2013
DOI 10.17305/bjbms.2013.2355
Pubmed ID
Authors

Nermana Mehić-Basara, Lilijana Oruč, Lejla Kapur-Pojskić, Jasmin Ramić

Abstract

There is a clear evidence that same psychoactive substance may cause various individual physiological reactions in same environmental conditions. Although there is a general attitude on equal liability to opioid addiction, latest genetic analysis findings imply there are certain quantifiable factors that could lead to elevated individual liability towards development of opioid addiction. The goal of this study was to investigate association of certain personality traits and genetic factors (separately and in combination) with heroin addiction. Total of 200 individuals participated in the study: 100 patients on Metadone Maintenance Treatment (MMT) and 100 age and sex matched healthy volunteers. All were medically examined, interviewed and psychologically evaluated using Eysenck personality questionnaire (EPQ) and genotyped for DRD2 (rs1800497) using PCR-RFLP method. Overrepresentation of certain personality traits (neuroticism, psychoticism and extraversion/ intraversion), together with environemental risk factors such as: upbringing within incomplete families and familial history of psychotropic substances abuse, are associated with high-risk development of opioid addiction.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 19%
Student > Doctoral Student 5 14%
Other 4 11%
Student > Ph. D. Student 3 8%
Professor > Associate Professor 3 8%
Other 8 22%
Unknown 6 17%
Readers by discipline Count As %
Medicine and Dentistry 11 31%
Agricultural and Biological Sciences 6 17%
Biochemistry, Genetics and Molecular Biology 4 11%
Neuroscience 3 8%
Psychology 2 6%
Other 4 11%
Unknown 6 17%