| Title |
Comparison of ordinal versus Agatston coronary calcification scoring for cardiovascular disease mortality in community-living individuals
|
|---|---|
| Published in |
The International Journal of Cardiovascular Imaging, March 2014
|
| DOI | 10.1007/s10554-014-0392-1 |
| Pubmed ID | |
| Authors |
Katherine J. Blair, Matthew A. Allison, Cindy Morgan, Christina L. Wassel, Dena E. Rifkin, C. Michael Wright, Michael H. Criqui, Joachim H. Ix |
| Abstract |
Coronary artery calcification (CAC) by the Agatston method predicts cardiovascular disease (CVD), but requires cardiac gated computed tomography (CT) scans, a procedure not covered by most insurance providers. An ordinal CAC score (scored 0-12 based on artery number and extent of calcification involvement) can be measured on standard chest CTs. However, the correlation of ordinal and Agatston CAC scores and their relative association with CVD mortality is uncertain, which we sought to determine. Nested case-control study. Community-living individuals undergoing "whole body" CT scans for preventive medicine. 4,544 consecutive patients with CT scans, were followed from 2000 to 2009. We selected cases who died of CVD (n = 57) and age, sex, and CT slice-thickness matched each case to three controls (N = 171). Cardiac gated 3 mm chest CTs and non-gated 6 mm standard chest CTs. CVD death over 9 years follow-up. The intra- and inter-reader kappa for the ordinal CAC score was 0.90 and 0.76 respectively. The correlation of Agatston and ordinal CAC scores was 0.72 (p < 0.001). In models adjusted for traditional CVD risk factors, the odds of CVD death per 1 SD greater CAC was 1.66 (1.03-2.68) using the ordinal CAC score and 1.57 (1.00-2.46) using the Agatston score. A simple ordinal CAC score is reproducible, strongly correlated with Agatston CAC scores, and provides similar prediction for CVD death in predominantly Caucasian community-living individuals. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Israel | 1 | 2% |
| United States | 1 | 2% |
| Czechia | 1 | 2% |
| Unknown | 42 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 18% |
| Researcher | 8 | 18% |
| Other | 6 | 13% |
| Student > Master | 6 | 13% |
| Student > Postgraduate | 4 | 9% |
| Other | 6 | 13% |
| Unknown | 7 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 49% |
| Nursing and Health Professions | 4 | 9% |
| Computer Science | 3 | 7% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 12 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2014.
All research outputs
#19,945,185
of 25,374,917 outputs
Outputs from The International Journal of Cardiovascular Imaging
#1,116
of 2,012 outputs
Outputs of similar age
#165,385
of 235,445 outputs
Outputs of similar age from The International Journal of Cardiovascular Imaging
#12
of 43 outputs
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