| Title |
The Skin-Resident Immune Network
|
|---|---|
| Published in |
Current Dermatology Reports, November 2013
|
| DOI | 10.1007/s13671-013-0063-9 |
| Pubmed ID | |
| Authors |
Szun S. Tay, Ben Roediger, Philip L. Tong, Shweta Tikoo, Wolfgang Weninger |
| Abstract |
The skin provides an effective physical and biological barrier against environmental and pathogenic insults whilst ensuring tolerance against commensal microbes. This protection is afforded by the unique anatomy and cellular composition of the skin, particularly the vast network of skin-associated immune cells. These include the long-appreciated tissue-resident macrophages, dendritic cells, and mast cells, as well as the more recently described dermal γδ T cells and innate lymphoid cells. Collectively, these cells orchestrate the defense against a wide range of pathogens and environmental challenges, but also perform a number of homeostatic functions. Here, we review recent developments in our understanding of the various roles that leukocyte subsets play in cutaneous immunobiology, and introduce the newer members of the skin immune system. Implications for human disease are discussed. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 213 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 3 | 1% |
| France | 2 | <1% |
| United States | 1 | <1% |
| Unknown | 207 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 17% |
| Researcher | 37 | 17% |
| Student > Master | 27 | 13% |
| Student > Bachelor | 18 | 8% |
| Other | 16 | 8% |
| Other | 36 | 17% |
| Unknown | 42 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 46 | 22% |
| Biochemistry, Genetics and Molecular Biology | 35 | 16% |
| Medicine and Dentistry | 35 | 16% |
| Immunology and Microbiology | 31 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
| Other | 17 | 8% |
| Unknown | 43 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2014.
All research outputs
#14,193,746
of 22,751,628 outputs
Outputs from Current Dermatology Reports
#53
of 120 outputs
Outputs of similar age
#176,457
of 306,674 outputs
Outputs of similar age from Current Dermatology Reports
#2
of 2 outputs
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So far Altmetric has tracked 120 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 54% of its peers.
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