Title |
HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial
|
---|---|
Published in |
Trials, March 2014
|
DOI | 10.1186/1745-6215-15-91 |
Pubmed ID | |
Authors |
Gerie J Glas, Johannes Muller, Jan M Binnekade, Berry Cleffken, Kirsten Colpaert, Barry Dixon, Nicole P Juffermans, Paul Knape, Marcel M Levi, Bert G Loef, David P Mackie, Manu Malbrain, Marcus J Schultz, Koenraad F van der Sluijs |
Abstract |
Pulmonary coagulopathy is a hallmark of lung injury following inhalation trauma. Locally applied heparin attenuates lung injury in animal models of smoke inhalation. Whether local treatment with heparin benefits patients with inhalation trauma is uncertain. The present trial aims at comparing a strategy using frequent nebulizations of heparin with standard care in intubated and ventilated burn patients with bronchoscopically confirmed inhalation trauma. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Argentina | 1 | 1% |
Canada | 1 | 1% |
Unknown | 95 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 16 | 16% |
Student > Postgraduate | 11 | 11% |
Student > Bachelor | 10 | 10% |
Researcher | 10 | 10% |
Student > Doctoral Student | 9 | 9% |
Other | 18 | 18% |
Unknown | 24 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 53 | 54% |
Nursing and Health Professions | 7 | 7% |
Agricultural and Biological Sciences | 4 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
Social Sciences | 2 | 2% |
Other | 2 | 2% |
Unknown | 26 | 27% |